口蓋裂の副鼻腔炎-アレルギーの関与について-

概要

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We examined if allergy is involved in the development of sinus infection in cleft palate patients. Furthermore, the rate of nasal polyps in these patients was also examined because nasal polyps have been reported to be closely related to allergy. Our subjects were 151 cleft palate patients with sinusitis, between 0 and 50 years old. The control group consisted of 406 non-cleft individuals with sinus infection, between 1 and 73 years old.The rate of allergic history was significantly lower in cleft palate patients with sinusitis than in the normal control (p<0.01). Cases with positive eosinophils in nasal secretions were significantly fewer in the cleft population with sinusitis than in the normal control (p<0.01). No significant difference between the two groups was observed in the incidence of eosinophilia in blood. The rate of nasal polyps was markedly lower in the cleft group with sinus infection than in the normal control. In patients with cleft palate, allergy seemed to play a minor role in the development of sinus infection compared to the normal population.
耳鼻咽喉科臨床学会の論文