Changes in clinical symptoms and Dermatophagoides pteronyssinus specific IgG antibodies during house dust hyposensitization therapy.
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Sera from patients who were currently undergoing house dust hyposensitization therapy were used to measure specific antibodies to Dermatophagoides pteronyssinus (DP). Simultaneously, the total IgE and specific IgE levels were determined. No significant differences in total IgE and specific IgE levels during immunotherapy were found between patients who had had remission of clinical symptoms and who had not. DP specific IgG levels were elevated only in patients who had a good clinical course. DP specific IgG levels began to elevate 2-4 months after therapy, but, there were differences in IgG levels before and after therapy among patients. Elevated DP specific IgG levels were observed at the time when the patients experienced relief from symptoms.
- 耳鼻咽喉科臨床学会の論文
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