頭頸部領域の同時重複癌

概要

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We treated 51 year-old male patient with six carcinomas: right margin of the tongue, left piriform sinus, left vocal cord, right side of the oral floor, left margin of the tongue and E-C junction of the esophagus. Histological examination revealed squamous cell carcinoma in all specimens. He had severe diabetes mellitus and gastric ulcer. Combination therapy with irradiation, antitumor agents and cryosurgery was given. He died of bleeding from his gastric ulcer during the course of treatment.Sixty cases, 44 males and 16 females, of synchronous multiple primary cancers of the head and neck have been reported in the Japanese literature. Of 60 multiple primary Carcinomata, laryngeal cancers were most frequent (18 cases), and antral cancers were next (14 cases).Cancers of both maxillary sinuses were most frequently seen, and double cancers of the larynx and lung, thyroid, hypopharynx and stomach were next most frequent. Sextuple primary carcinomata as described here has not previously been reported in the Japanese literature.
耳鼻咽喉科臨床学会の論文