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The two patients were males, 26 and 21 years of age.The clinical manifestations were fever, sore throat, cervical lymph node enlargement and severe tonsillitis. Atypical lymphocytes, over 10 percent, were found in both patients' peripheral blood. Both had impaired liver function and positive Paul-Bunnell tests (high titer of heterophile agglutinin), with a specific Davidsohn reaction. The suspected etiology was Epstein Barr virus, since the titers of anti-V. C. A. (viral capsid antigen) antibody were 1:40 and 1:160.There was little response to antibiotics and steroids, but both patients gradually improved.
- 耳鼻咽喉科臨床学会の論文
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