Role of atopic allergy in otitis media with effusion - A clinical observation.:A Clinical Observation

概要

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The allergic etiology of otitis media with effusion (OME) is still a controversial topic. Many investigators have reported a high incidence of OME in allergic patients, but an allergic etiology has been denied by others because of a lack of direct scientific evidence proving that the middle ear effusion is an allergic product. To clarify the role of IgE mediated allergy in OME, we studied 97 patients with OME and 370 patients with nasal allergy with routine allergy tests evaluation of hearing and middle ear function and pneumatic otoscopy. A positive allergen skin test was found in 47 of 97 (49%) patients with OME. Allergy tests demonstrated that 25 of 97 (26%) patients with OME had clinically symptomatic nasal allergy. Eardrum examination, hearing tests, and impedance audiometry revealed that 7 of 370 (2%) patients with nasal allergy had OME. The discrepancy between the two groups could not be explained, but it is suspected that subclinical allergy is one of the causative or promotive factors of OME. Further investigations are needed.
耳鼻咽喉科臨床学会の論文