The influence of the overload to the epiphyseal growth an experimental study.

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To investigate the influence of the overload to the epiphyseal growth, fifty-two rabbits, ten to fourteen days old, had the left ulnar diaphysis excised and for the radiological and histological studies of the radius were killed at variable time interval from the second to the 35th postoperative day. Following results were obtained. 1. Within 12 days tilt of radial epiphysis towards the palm and curvature of radius towards the ulna were produced. 2. Following 2 weeks, tilt, curvature, size of the epiphysis and length of radius decreased, probably due to the synostosis of ulna. 3. At histological study ulnar side of epiphyseal plate showed short proliferative cell column and the hypertrophic cell grouped into the clusters or augmentation of the height of the base of the columnar layer. Radial side demonstrated few changes or a fissure passing within the enchondral ossification at which epiphyseal side showed augmentation of the columnar layer.