両側下顎日歯部に発生した巨細胞修復性肉芽腫の1経験例ならびに病理組織学的, 文献的考察

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Giant cellular lesions are characterized by the presence of multinuclear cells, and those known to develop in the intramaxillary regions include giant cytoma, giant cellular granuloma, brown tumor, Cherubism, etc.<BR>Modifiable giant cellular granuloma that were advanced by Jaffe (1953) have been treated as giant cellular epulis or giant cellular granuloma, which develops in a perimaxillary region, and central giant cellular granuloma which develops in an intramaxillary region.<BR>As we experienced suspected the central giant cellular modifiable granuloma in a 6.7-year old boy that developed in the bilateral mandibular molar regions, we report our pathological findings in addition to some discussions on the published literatures.<BR>The diagnosis in this patient was established as central giant cellular modifiable granuloma, although the symptoms initially suspected as Cherubism were neither clinically nor genetically confirmed.