Clinical significances of chronic schistosomiasis japonica-histological detection of ova of schistosoma japonicum.

概要

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Histological examination for ova of schistosoma japonicum was performed in surgical specimens of laparotomy during 20 months from Oct., 1983 to May, 1985, in the 1st Department of Surgery, Yamanashi Medical College. Calcified schistosomal ova were detected in 54 cases out of 282, and its ratio, 19.1%, was higher than that of previous reports in Japan, including Yamanashi Prefecture. Organ distribution of ova was observed as follows; high incidences in liver (22.5% in all cases), duodenum (22.7%), colon and rectum (18.8%), and stomach (17.2%). No ova were detected in bile tract (108 cases), spleen (31 cases), and esophagus (31 cases). Among these 54 cases of chronic schistomomiasis japonica, 22 cases of liver fibrosis and 5 cases of liver cirrhosis in which 3 cases accompanied hepatocellular carcinoma. It suggests an epidemiological relationship between schistosomiasis japonica and hepatocellular carcinoma.According to Japan Autopsy Annual in Yamanashi Prefecture for 10 years (1973-1982), schistosomiasis japonica was accompanied in 20.5% of patients.
財団法人日本消化器病学会の論文