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Six hundred and forty specimens of the resected stomach of patients with gastric disorders were examined histologically for lymphoid hyperplasia (LH). The LH was observed in 91 specimens, in which a spread pattern of LH outside the lesion (so-called RLH) was found in 20 cases, whereas an overlap pattern of LH on the lesions of ulcer or cancer, which was looked just like a reaction to the lesion, was found in 71 cases (45 in ulcer and 26 in cancer).In ulcer with LH, LH was present in the bottom of the ulcer or in the muscularis mucosa and showed a close relation to the hardness of ulcer-healing. In cancer with LH, LH was present only in the depressed type of cancer and showed characteristic patterns in the macroscopic and histologic findings of the lesion and also in the mode of submucosal infiltration.From these observations, the lesion of both ulcer and cancer associated with such reactive LH was considered as one of special types of ulcer and cancer in the stomach.
財団法人日本消化器病学会の論文