農村在住者の血清lipoprotein分画値に関する研究

概要

論文の詳細を見る
The method of Chin-Blankenhorn for serum lipoprotein electrophoresis on cellulose acetate was examined for possible use in screening hyperlipoproteinemia. The procedure was rapid and reproducible. This technique provided a complete resolution of α, pre β and β lipoproteins into district bands, but it was not truly quantitative, since it allowed estimation only of relative quantities of lipoproteins; each fraction was expressed as a percentage of the total lipid-staining method.In July 1972, determination of serum lipoproteins was made on 430 clinically healthy subjects, 147 men and 283 women, living at a rural area in Japan.1. It was difficult to establish the distribution type for the relative proportions of the three lipoproteins.2. The mean of α lipoprotein level decreased and that of β lipoprotein level increased with age in both sexes.3. In men, the mean of pre β lipoprotein level increased with age, reaching the maximum at the age of 40-49, after which it decreased. In women, the rise continued with age, but with a slight decrease at the age of 70 and over.4. The age and sex pattern for pre β lipoprotein was in accordance with that for triglyceride. A significant correlation was obtained between pre β lipoprotein and triglyceride, too.5. 18% (m+σ), a relative quantity of pre β lipoprotein, was recommended as a criterion for the diagnosis of a borderline hyper-pre-β-lipoproteinemia and 26% (m+2σ) as a criterion for the diagnosis of a hyper-pre-β-lipoproteinemia.6. Densitometric tracing patterns of serum lipoprotein electropherogram were classified as follows; Types A1, A2, A3, A4, B, C and D. The frequency of Type A1, a typical normal type, decreased with age in both sexes.
日本衛生学会の論文

農村在住者の血清lipoprotein分画値に関する研究

スポンサーリンク

概要

著者

関連論文

スポンサーリンク