Intravascular Large B-Cell Lymphoma Associated with t(14;19)(q32;q13) Translocation
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概要
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We report a 59-year-old man with intravascular large B-cell lymphoma (IVLBCL) associated with hemophagocytic syndrome, disseminated intravascular coagulopathy, and lung involvement. G-banding analysis of the metaphase spreads obtained from the bone marrow showed that the lymphoma cells were near-tetraploid and included two homologues of the 14q+ chromosome. Spectral karyotyping revealed that complex translocations occurred among chromosomes 3, 12, 14, and 19, and additional materials of 14q+ were from chromosome 19 with the breakpoint at 14q32 and 19q13. To the best of our knowledge, this is the first report describing t(14;19)(q32;q13) in IVLBCL.
- 社団法人 日本内科学会の論文
著者
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Kobayashi Taishi
Department Of Nuclear Engineering Kyoto University
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Ohno Hitoshi
Department Of Hematology And Oncology Clinical Sciences For Pathological Organs Graduate School Of M
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