Microbial Conversion of Curcumin into Colorless Hydroderivatives by the Endophytic Fungus Diaporthe sp. Associated with Curcuma longa

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概要

• 論文の詳細を見る

• We investigated the microbial conversion of curcumin (1) using endophytic fungi associated with the rhizome of Curcuma longa (Zingiberaceae). We found that Diaporthe sp., an endophytic filamentous fungus, converts curcumin (1) into four colorless derivatives, namely (3R,5R)-tetrahydrocurcumin (2), a novel (3R,5S)-hexahydrocurcumin (3) named neohexahydrocurcumin, (3S,5S)-octahydrocurcumin (4) and meso-octahydrocurcumin (5).

著者

• OHASHI Kazuyoshi

  Faculty of Pharmacy and Parmaceutical Sciences, Fukuyama University

• MAEHARA Shoji

  Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University

• Shibuya Hirotaka

  Faculty Of Pharmaceutical Sciences Fukuyama University

• Kitamura Chinami

  Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University

• Haraguchi Hiroyuki

  Faculty Of Engineering Fukuyama University

• Ikeda Michiteru

  Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University

• Nagoe Tetsuro

  Rohokeimeido Co., Ltd.

• Ohashi Kazuyoshi

  Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University

• Haraguchi Hiroyuki

  Faculty of Life Science and Biotechnology, Fukuyama University

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