Biooxidation of (+)-Catechin and (-)-Epicatechin into 3,4-Dihydroxyflavan Derivatives by the Endophytic Fungus Diaporthe sp. Isolated from a Tea Plant
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概要
- 論文の詳細を見る
The microbial transformation of (+)-catechin (1) and (-)-epicatechin (2) by endophytic fungi isolated from a tea plant was investigated. It was found that the endophytic filamentous fungus Diaporthe sp. transformed them (1, 2) into the 3,4-cis-di-hydroxyflavan derivatives, (+)-(2R,3S,4S)-3,4,5,7,3',4'-hexahy-droxyflavan (3) and (-)-(2R,3R,4R)-3,4,5,7,3',4'-hexahydroxy-avan (7), respectively, whereas (-)-catechin (ent-1) and (+)-epicatechin (ent-2) with a 2S-phenyl group resisted the biooxidation.
- 公益社団法人日本薬学会の論文
- 2005-07-01
著者
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渋谷 博孝
福山大学
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下田 博司
森下仁丹株式会社商品開発本部
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シマンジュンタク パルトムアン
大阪大学薬学部
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Ohnishi K
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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SHIBUYA Hirotaka
Faculty of Pharmacy and Parmaceutical Sciences, Fukuyama University
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OHASHI Kazuyoshi
Faculty of Pharmacy and Parmaceutical Sciences, Fukuyama University
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Ohnishi Kazunori
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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MAEHARA Shoji
Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University
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SIMANJUNTAK Partomuan
Research Centre for Biotechnology Indonesian Institute of Sciences
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シマンジュンタク パルトムアン
福山大学
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Shibuya H
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Shibuya H
Faculty Of Pharmaceutical Sciences Osaka University
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Shibuya H
Fukuyama Univ. Hiroshima Jpn
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Shibuya Hirotaka
Faculty Of Pharmaceutical Sciences Fukuyama University
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Agusta Andria
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
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Omachi Ken
Department Of Hematology And Oncology Tokai University School Of Medicine
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Odagiri Keiichi
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Simanjuntak P
Osaka Univ. Osaka Jpn
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Ohnishi Kazunori
The Department Of Medicine Iii Hamamatsu University School Of Medicine
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Ohashi K
Third Department Of Internal Medicine Hamamatsu University School Of Medicine
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Simanjuntak Partomuan
Research Center For Biotechnology Indonesian Institute Of Sciences
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