ACTH, GH, Prolactin, and α-MSH Activities of Six kinds of Cells Isolated from the Rat Adenohypophysis
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概要
- 論文の詳細を見る
The six kinds of cells, viz. chromophobes, ambiguous cells, acidophilic and basophilic intermediate cells, typical acidophils and basophils, were isolated from the rat fresh anterior pituitaries by the procedure of Ishikawa (1969) with some modifications. Bioassays of ACTH, prolactin, and a-MSH, and radioimmunoassay of GH were carried out for a mass of each isolated cell type. The chromophobes showed no hormonal activity. The ambiguous cells contained only α-MSH. Both ACTH and GH were localized predominantly in the acidophilic intermediate cells and typical acidophils, but prolactin was found only in the latter. Only a trace amount of ACTH, GH, and prolactin was found in the basophilic intermediate cells and typical basophils. It was elucidated that the cells on the acidophilic axis were involved in the producing cells of ACTH.
- 社団法人 日本内分泌学会の論文
著者
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Watanabe Teruko
Department Of Life Science Faculty Of Bioresources Mie University
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Yoshimura Fujio
Department Of Anatomy Jikai University School Of Medicine
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Ishikawa Hiroshi
Department Of Anatomy Jikei University School Of Medicine
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