Sexual Cyclicity and Diurnal Corticosterone Secretion in Rats Given Hypothalamic Transection at Two Days of Age
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概要
- 論文の詳細を見る
Female rats given neural transection between suprachiasmatic and arcuate nuclei at 2days of age showed regular sexual cyclicity and had ovarian corpora lutea. Thus, the ovarian activity seemed identical to that of intact or sham-operated control rats. However, the diurnal rhythm of the blood corticosterone concentration of the neonatally transected rats was not evident at 22days of age, while it was already evident in controls. At 30 and 50days of age, they had clear adrenal rhythms although the peak values were significantly lower than those of controls. Thus, the anterior connections of the medial basal hypothalamus, which are necessary for both cyclic gonadotropin discharge and diurnal corticosterone secretion, are still plastic and not yet established at 2days of age.
- 社団法人 日本内分泌学会の論文
著者
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Miyabo Susumu
Department Of Cardiovascular System Maizuru Kyosai Hospital
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Hayashi Shinji
Department Of Anatomy And Embryology Tokyo Metropolitan Institute For Neuroscience
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HISADA TOMOICHIRO
Department of Internal Medicine, School of Medicine, Kanazawa University
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OOYA EIICHI
Department of Internal Medicine, School of Medicine, Kanazawa University
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MIYABO SUSUMU
Department of Internal Medicine, School of Medicine, Kanazawa University
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