Molecular Shape of Dystrophin with Special References to Type VI Collagen.
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概要
- 論文の詳細を見る
We have reported a dumbbell-shaped structure of dystrophin molecule (Murayama et al., 1990; Sato et al., 1992). However its small population has raised a possibility that the dumbbell structure was due to a contaminant protein, such as type VI collagen of aorta origin. In the present study, type VI collagen was purified from bacterial collagenase-treated aorta of the rabbit. Its rotary shadowed images were very similar to those present in the dystrophin preparations. However, the antiserum to type VI collagen raised in a mouse did not react with dystrophin samples. A tentative explanation for the small population of the dumbbell structure is described.
- 日本学士院の論文
著者
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Kimura Sumiko
Department Of Anatomy And Developmental Biology Kyoto University
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Maruyama Koscak
Department of Biology, Faculty of Science, Chiba University
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Maruyama Koscak
Department Of Biology Faculty Of Science Chiba University
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Sato Osamu
Department Of Agricultural Chemistry Faculty Of Agriculture Nagoya University
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KAKE Takei
Department of Biology, Faculty of Science, Chiba University
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SPISSINGER Thomas
Abteilung Biophysical Chemistry, Biocenter, University of Basel
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