Fluoroscopic contrast medium percutaneous ethanol injection therapy(FCM-PEIT) to hepatocellular carcinoma: Comparison between ultrasound image and X-ray findings.

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In order to investigate whether the ultrasound (US) images of hepatocellular carcinoma (HCC) nodules correctly reflect the kinetics of ethanol in the HCC nodules during percutaneous ethanol injection therapy (PEIT), we compared those images with the X-ray findings in fluoroscopic contrast medium PEIT (FCM-PEIT, total 213 injections in 76 HCC nodules, 10 to 81mm i.d., 54 patients). FCM-PEIT has been previously reported from our groups as a new approach to obtain accurate kinetics of ethanol in the HCC nodule by mixing with contrast medium (Iopamidol containing 370mg/dl iodine, vol/vol; 7/3). The X-ray findings correctly reflected to the kinetics of ethanol. The US images were divided into two types during the quarter injection of the entire volume of the contrast medium-mixed ethanol (CME): patchy ECHO (95 times) and uniform ECHO image (118 times). These US images, while, did not change during the quarter to the end (144 times) and during the half or 3/4 to the end of the CME injection (69 times), despite of the increase of the CME inflow into the HCC nodule. HCC nodules of patchy ECHO at the end of the CME injection, was significantly larger than those of uniform ECHO (p<0.001). From types of the US images during CME injections, we were not able to judge whether CME was evenly injected into the whole HCC nodule. The present results suggest that the US image dose not reflect correctly to the kinetics of injected ethanol into the HCC nodule.
社団法人日本肝臓学会の論文

Fluoroscopic contrast medium percutaneous ethanol injection therapy(FCM-PEIT) to hepatocellular carcinoma: Comparison between ultrasound image and X-ray findings.

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