A Proposed Strategy for Treatment of Superficial Carcinoma in the Thoracic Esophagus Based on an Analysis of Lymph Node Metastasis.

スポンサーリンク

概要

• 論文の詳細を見る

• Background and Aims : To determine the optimal treatment of superficial carcinoma of the thoracic esophagus, we retrospectively analyzed the site and prevalence of lymph node metastases in three-field dissection specimens removed during radical esophagectomy.<BR>Methods : We reviewed the medical charts and surgical and histopathological reports of 34 patients with superficial carcinoma of the thoracic esophagus, who were treated with esophagectomy and three-field lymph node dissection.<BR>Results : Lymph node metastases were found in 14 of 34 patients (41%). None of five cases with tumor invasion of only the pEP or pLPM had lymph node metastases. However, the prevalence of lymph node metastases from tumors that invaded the pMM or pSM was 22% and 60%, respectively. Even when the cancer was located in the lower esophagus, the prevalence of cervical lymph node metastases was 20%. Two of three (67%) patients had cervical lymph node metastases even when there were no metastases in mediastinal nodes ("jumping lymph node metastases"). The 5-year survival rates in patients with and without lymph node metastases were 83% and 100%, respectively.<BR>Conclusions : A radical esophagectomy with three-field lymph node dissection should be performed on patients who have superficial carcinoma of the thoracic esophagus that invades the pMM or deeper.

• 北関東医学会の論文

著者

• Takeyoshi Izumi

  Second Department Of Surgery Gunma University School Of Medicine

• Kusano Motoyasu

  Department Of Endoscopy And Endoscopic Surgery Gunma University Hospital

• Ohwada Susumu

  Second Department Of Surgery Faculty Of Medicine Gunma University

• KAWATE SUSUMU

  Second Department of Surgery, Gunma University Faculty of Medicine

• TOMIZAWA NAOKI

  Second Department of Surgery, Gunma University Faculty of Medicine

• Kawamura Osamu

  Department Of Animal And Grassland Science Faculty Of Agriculture University Of Miyazaki

• Nakamura Seiji

  Second Department Of Oral And Maxillofacial Surgery Faculty Of Dentistry Kyushu University

• Morishita Yasuo

  Second Department Of Surgery

• Ogawa Tetsushi

  Second Department of Surgery, Gunma University Faculty of Medicine

• Kawamura Osamu

  Department of Endoscopy and Endoscopic Surgery, Gunma University Hospital

• Okano Takao

  Second Department of Surgery, Gunma University Faculty of Medicine

• Kawasima Yoshiyuki

  Second Department of Surgery, Gunma University Faculty of Medicine

• Takeyoshi Izumi

  Second Department of Surgery, Gunma University Faculty of Medicine

• Ohwada Susumu

  Second Department of Surgery, Gunma University Faculty of Medicine

• Nakamura Seiji

  Second Department of Surgery, Gunma University Faculty of Medicine

関連論文

• SF-107-4 大腸sm癌のリンパ節転移と遺伝子群のマイクロアレイによる解析(第107回日本外科学会定期学術集会)
• SY-1-2-5 肝細胞癌の進展機構解析による新規分子標的の同定(シンポジウム1-2 消化器癌の発生機序から見た治療戦略-肝胆膵癌,第62回日本消化器外科学会定期学術総会)
• 発がん・増殖 BRCA遺伝子機能とその機能欠損による乳癌発生機序 (乳癌--基礎と臨床の架け橋)
• 図説 最新のゲノムワイド解析技術 (特集 ゲノム研究最前線--疾患ゲノム研究の現状と展望)
• IS-3-4 乳がん術前化学療法の効果予測システム開発の試み(第108回日本外科会定期学術集会)
• A Japanese patient with Li-Fraumeni syndrome who had nine primary malignancies associated with a germline mutation of the p53 tumor-suppressor gene
• SF-108-2 大腸癌先進部脱分化に関与する遺伝子群の同定と機能ネットワークの構築(第107回日本外科学会定期学術集会)
• O-109 原発性肺癌切除時の開胸時胸腔内洗浄液における微量肺癌細胞の検出と細胞診の比較(肺癌と分子生物学2, 第47回日本肺癌学会総会)
• DP-009-4 包括的遺伝子発現解析による膵癌リンパ節転移予測マーカーの同定(第108回日本外科学会定期学術集会)
• Cross-sectional analysis of germline BRCA1 and BRCA2 mutations in Japanese patients suspected to have hereditary breast/ovarian cancer
• P-7 原発性肺癌切除時の開胸時胸腔内洗浄液におけるCEA-mRNAの検出の意義(一般演題(ポスター) トランスレーショナルリサーチ,第48回日本肺癌学会総会)
• Bilateral Coronary Ostial Stenosis and Aortic Regurgitation due to Syphilitic Aortitis
• A Second Mitral Valve Replacement in a Patient With Hereditary Hemorrhagic Telangiectasia (Oslers Disease)
• Early Results and Operative Considerations of Endoventricular Circular Patch Plasty for Ischemic Cardiomyopathy
• PJ-604 Mechanism of Prevention of Transplant Arteriosclerosis by Mycophenolate Mofetil in a Rat Aortic Allograft Model(Transplantation 2 (M) : PJ101)(Poster Session (Japanese))
• Histological Features of Breast Cancer, Highly Sensitive to Chemotherapy
• Identifying haplotype block structure using an ancestor-derived model
• High proportion of missense mutations of the BRCA1 and BRCA2 genes in Japanese breast cancer families
• Use of an Intratracheal Silicone Prosthesis (Dumon Type) for the Treatment of Tracheoesophageal Fistula Due to Advanced Lung Cancer
• A Hemophagocytic Syndrome-Like Condition After Emergency Colectomy for Perforated Colon Cancer : Report of a Case
• Clinical Results of Extracorporeal Membrane Oxygenation (ECMO) Support for Acute Respiratory Failure : A Comparison of a Centrifugal Pump ECMO with a Roller Pump ECMO
• Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma : A Case Report
• Two Case of Breast Cancer with Cartilaginous and Osseous Metaplasia
• Long-Term Suppression of Lymphangitic Lung Metastasis from Breast Cancer Using Biweekly Docetaxel : A Case Report
• Thyroid Carcinoma with Internal Jugular Vein Thrombus : Report of a Case
• Breast-Conserving Therapy Versus Modified Radical Mastectomy in the Treatment of Early Breast Cancer in Japan
• Tamoxifen-Failed Male Breast Cancer with a High Level of Circulating Estrogen : Report of a Case
• Recurrence of Breast Cancer Following Local Excision Alone for Ductal Carcinoma in situ
• A Case Report of Advanced Male Breast Cancer with an Objective Response to Tamoxifen Treatment
• Trends of IL-6 and IL-8 Levels in Patients with Recurrent Breast Cancer: Preliminary report
• Percutaneous ethanol injection therapy for patients with inoperable thyroid papillary cancer: a report of two cases
• The Efficacy of Technetium-99m-MIBI Scan and Intraoperative Mehylene Blue Staining for the Localization of Abnormal Parathyroid Glands
• Granular Cell Tumor of the Breast Diagnosed by Core Needle Biopsy: A Case Report
• A New Endocrine Therapy strategy for Bone Metastasis of Breast Cancer : The Effect of Biological Response Modifiers and 22-Oxacarcitriol on Animal Models
• A Case Report of Lactating Adenoma of the Breast and Review of the Literatures in Japan
• Sudden Hemorrhage of the Breast Caused by Breast Cancer Without Skin Invasion: Report of a Case
• Screening for Abdominal Aortic Aneurysm and Occlusive Peripheral Vascular Disease in Japanese Residents
• 遺伝子診断の展望 (乳癌--基礎・臨床研究のアップデート) -- (臨床研究 診断 遺伝子診断)
• Functional pathway characterized by gene expression analysis of supraclavicular lymph node metastasis-positive breast cancer
• Multidrug-resistant Recurrent Breast Cancer Which Responded to Medroxyprogesterone Acetate Showing a Remarkable Improvement in the Quality of Life : Report of a Case and the Role of Team Medical Care
• Efficacy of Nyoshinsan/TJ-67, a traditional herbal medicine, for menopausal symptoms following surgery and adjuvant chemotherapy for premenopausal breast cancer
• Improved In-Gel Competitive Reassociation technique can detect Epstein-Barr virus genome in gastric cancer
• Surgical Treatment with Deep Hypothermia for Thoracic Aortic Aneurysm in a Patient with Renal Transplantation
• Gastrointestinal Complications after Cardiovascular Surgery with Cardiopulmonary Bypass
• Mitral Regurgitation With an Isolated Anterior Mitral Leaflet Cleft : A Case Report
• Screening Cost for Abdominal Aortic Aneurysms : Japan-Based Estimates
• Hemodynamic and Metabolic Effects of Hypertonic Saline Infusion in Normovolemic Dogs
• Surgical Treatment for Inflammatory Abdominal Aortic Aneurysm
• Pericardiectomy to Treat Constrictive Pericarditis in a Patient with Hyperbilirubinemia : Report of a Case
• Blood Cardioplegia Recovers Myocardial Viability after Simple Cold Immersion in Long-term Heart Preservation
• The Use of Radial Artery as the Second Arterial Graft for Coronary Artery Bypass Grafting
• Solitary Skin Metastasis After Lung Cancer Resection
• Endobronchial Lipoma Accompanied with Primary Lung Cancer : Report of a Case
• Postoperative Brain Complications Following Retrograde Cerebral Perfusion
• Thoracoscopic Closure of a Congenital Partial Pericardial Defect
• Arterial Embolization as Preoperative Treatment for Pulmonary Aspergillosis with Hemoptysis
• Use of Ultrasound-Guided Percutaneous Needle Biopsy in the Diagnosis of Mediastinal Tumors
• Extracorporeal Membrane Oxygenation for Respiratory Failure
• A Clinicopathologic Study of Breast Cancer Patients during Pregnancy
• Fibromyxoma of the Rib: Report of a Case
• Pulmonary Small Cell Carcinoma Associated with Sarcoid Reactions: Report of a Case
• Gastroptosis is Associated with Less Dyspepsia, Rather than a Cause of Dyspepsia, in Japanese Persons
• High Prevalence of Gastroesophageal Reflux Disease with Minimal Mucosal Change in Asthmatic Patients
• A Proton Pump Inhibitor, Lansoprazole, Ameliorates Asthma Symptoms in Asthmatic Patients with Gastroesophageal Reflux Disease
• Development and evaluation of FSSG : frequency scale for the symptoms of GERD
• NUMERICAL MODIFICATION OF THE LOS ANGELES CLASSIFICATION OF GASTROESOPHAGEAL REFLUX DISEASE FAILS TO DECREASE OBSERVER VARIATION
• Pulmonary Pleomorphic Liposarcoma
• Male Breast Cancer with Nipple Erosion : A Case Report
• Induction of a Critical Elevation of Povidone-Iodine Absorption in the Treatment of a Burn Patient: Report of a Case
• Isolation and characterization of cDNA encoding cinnamyl alcohol dehydrogenase (CAD) in sorghum (Sorghum bicolor (L.) Moench)
• Nationwide epidemiological study on gastroesophageal reflux disease and sleep disorders in the Japanese population
• Warthin's Tumour of the Parotid Glands, Adenomatous Hyperplasia and Oncocytic Adenomatous Hyperplasia of the Intranodal Heterotopic Salivary Glands : A Comparative Immunohistochemical Assessment
• Ileal Perforation Caused by Cytomegalovirus Infection in a Patient with Recurrent Gastric Cancer : Report of a Case
• RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR ACCELERATES REGENERATION AFTER T-2 TOXIN-INDUCED HEMOPOIETIC INJURY AND LESSENS LETHALITY IN MICE
• New Frontiers in Gut Nutrient Sensor Research: Monosodium L-Glutamate Added to a High-Energy, High-Protein Liquid Diet Promotes Gastric Emptying: a Possible Therapy for Patients With Functional Dyspepsia
• Increased Choline Kinase Activity and Elevated Phosphocholine Levels in Human Colon Cancer
• A CASE OF CA19-9-PRODUCING ADENOCARCINOMA OF THE REMNANT STOMACH RESEMBLING GASTRITIS CYSTICA POLYPOSA
• Structure and expression profile of the cinnamyl alcohol dehydrogenase gene and its association with lignification in the sorghum (Sorghum bicolor (L.) Moench) bmr-6 mutant
• Successful Resection of a Retroperitoneal Malignant Fibrous Histiocytoma with Caval Tumor Thrombus
• Isolated Chylopericardium Following Radical Esophagectomy : Report of a Case
• Small ileal neurofibroma causing intussusception in a non-neurofibromatosis patient
• Increased Choline Kinase Activity in 1,2-Dimethylhydrazine-induced Rat Colon Cancer
• A double-blind, controlled study comparing lafutidine with placebo and famotidine in Japanese patients with mild reflux esophagitis
• Primary Hepatic Leiomyosarcoma with Giant Cyst Formation : A Case Report
• Effects of a Phosphate Buffered Extracellular (Ep4) Solution in Preservation and Reperfusion Injury in the Canine Liver
• Enteropathy-type T-cell Lymphoma that was Pathologically Diagnosed as Celiac Disease
• New Frontiers in Gut Nutrient Sensor Research : Monosodium L-Glutamate Added to a High-Energy, High-Protein Liquid Diet Promotes Gastric Emptying : a Possible Therapy for Patients With Functional Dyspepsia
• Histochemical Studies on the Rumen Digestion of Rice Straw Cell Wall and on the Chemical Determination of Its Non Nutritive Residue
• Survey on the prevalence of GERD and FD based on the Montreal definition and the Rome III criteria among patients presenting with epigastric symptoms in Japan
• A new index of severe reflux esophagitis : what does the minimum LES pressure represent?
• Effect of rabeprazole treatment on health-related quality of life and symptoms in patients with reflux esophagitis : a prospective multicenter observational study in Japan
• What is the difference between GEFV and HH?
• Investigation of pretreatment prediction of proton pump inhibitor (PPI)-resistant patients with gastroesophageal reflux disease and the dose escalation challenge of PPIs-TORNADO study : a multicenter prospective study by the Acid-Related Symptom Research
• Rikkunshito improves symptoms in PPI-refractory GERD patients : a prospective, randomized, multicenter trial in Japan
• Combination of angiotensin II receptor blockers promotes proton pump inhibitor-based healing of reflux esophagitis
• Patterns of lymph node metastasis in three-field dissection for thoracic esophageal carcinoma. Optimal extension of lymph node dissection.:OPTIMAL EXTENSION OF LYMPH NODE DISSECTION
• A Proposed Strategy for Treatment of Superficial Carcinoma in the Thoracic Esophagus Based on an Analysis of Lymph Node Metastasis.
• The Effects of Steroids on Pulmonary Ischemia-Reperfusion Injury in Dogs.
• Concomitant laparoscopic treatment for primary aldosteronism and cholelithiasis.
• The effect of fertilizer and manure application on CH_4 and N_2O emissions from managed grasslands in Japan(Mitigation of methane and nitrous oxide emissions from agricultural lands)

もっと見る 閉じる

スポンサーリンク