THE EFFECTS OF DRUGS ON THE PRODUCTION AND RECOVERY PROCESSES OF THE STRESS ULCER
スポンサーリンク
概要
- 論文の詳細を見る
Various procedures have been reported on the biossay of antiulcer drugs . Pylorus ligation of the rat (1-3), restraint of the rat (4, 5), water immersion of the restrained rat (7) and the application of ulcerogenic agents on various animals (8-11) were used for producing experimental ulcers. In these methods the drug had been administered to the animal before the ulcer production and the preventive effect on the ulcer producing processes was tested. Although some drugs such as glutamine or methylmethionine sulfonium chloride were recently introduced to promote the repair of the ulcer which had existed already, suitable methods are lacking for their pharmacological test, and so it was hoped to develop a new method for pharmacological assay of curative activity of the drugs on existing ulcers. In the present paper curative effects of some drugs on the stress ulcer of the rat are reported.
- 社団法人 日本薬理学会の論文
著者
-
高木 敬次郎
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences University Of Tokyo:(present
-
岡部 進
Department Of Applied Pharmacology Kyoto Pharmaceutical University
-
岡部 進
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences University of Tokyo
-
高木 敬次郎
Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences University of Tokyo
関連論文
- Pharmacological Studies of Panacis Japonici Rhizoma. II
- Pharmacological Studies of Panacis Japonici Rhizoma. I
- Effect of Terephthalic Acid on the Blood Level of Sulfaethylthiadiazole.
- Atropine-like Activities of 2-Substituted 5-Piperidinomethylfuran Derivatives
- Studies on the Drugs for Peptic Ulcer. A Reliable Method for Producing Stress Ulcer in Rats.
- Studies on the Drugs for Peptic Ulcer. Pharmacological Studies on the Effects of Synthetic Antispasmodics mixed with Antacid.
- Effect of Anti-ulcer Drugs on Gastric Mucous Hexosamine in Rats subjected to Several Ulcerogenic Conditions
- Coronary Vasodilating Effect of Some Chromanone Derivatives
- Changes in Catecholamine Levels of Mouse Brain during Oscillation-stress
- Synthesis and Structure-Activity Relationship sof N-Substituted 2-[(2-Imidazolylsulfinyl)methyl]anilines as a New Class of Gastric H^+/K^+-ATPase Inhibitors
- Anti-inflammatory Activities of Hederagenin and Crude Saponin isolated from Sapindus mukorossi GAERTN
- Effects of Some Vasoactive Agents on Isolated Blood Vessels from Cholesterol-fed Rabbits
- Vasodilating Effect of Diphenylalkanolamines in Anesthetized Dogs
- Cardiovascular Effects of Some Peptide Analogues consisting of Cystine and/or Tyrosine
- Studies on Analgesics. IV. A Recording Apparatus for Pain Reaction on the Hot Plate.
- EFFECT OF CALCIUM IONS AND PHOSPHOLIPIDS ON ANTIACETYLCHOLINE ACTION OF ACETONE AND PAPAVERINE
- ACTIONS OF DOPAMINE AND ITS DERIVATIVES ON THE TAENIA CAECUM AND TRACHEAL MUSCLE FROM THE GUINEA PIG AND THE VAS DEFERENS FROM THE RAT
- THE EFFECT OF PROPRANOLOL ON THE STRESS AND SHAY ULCERATIONS IN RATS
- PHARMACOLOGICAL EXPERIMENTS WITH THE ISOLATED EXTRAOCULAR MUSCLE FROM RABBIT
- EFFECTS OF SUBCELLULAR FRACTIONS OF THE DOG SMALL INTESTINAL SMOOTH MUSCLE ON ACETYLCHOLINE-INDUCED CONTRACTION OF GLYCEROL EXTRACTED SKELETAL MUSCLE
- PURIFICATION OF HISTAMINE RECEPTOR IN CAT SMALL INTESTINAL MUSCLE : I) SPECIFICITY OF LABELING HISTAMINE RECEPTOR WITH RADIOACTIVE DIBENAMINE
- A POTENT COMPETITIVE INHIBITOR OF 5-HYDROXY-TRYPTAMINE: 3-(2-BENZYLAMINOETHYL)-5-METHOXYINDOL HYDROCHLORIDE
- THE EFFECTS OF CHOLINE AND ITS ANALOGUES ON THE OUTPUT OF ACETYLCHOLINE FROM THE ISOLATED ILEUM OF THE GUINEA PIG
- BETA-ADRENERGIC BLOCKER, 2-(2-HYDROXY-3-TERT-BUTYLAMINOPROPOXY) CHLOROBENZENE HYDROCHLORIDE (D-69-12)
- BETA-ADRENERGIC RECEPTORS IN VARIOUS ORGANS
- MODE OF ACTION OF PARTIAL AGONISTS ON THE TAENIA CAECUM OF THE GUINEA PIG AND DRUG-RECEPTOR THEORY
- THE EFFECTS OF DRUGS ON THE PRODUCTION AND RECOVERY PROCESSES OF THE STRESS ULCER
- A NEW METHOD FOR THE PRODUCTION OF CHRONIC GASTRIC ULCER IN RATS AND THE EFFECT OF SEVERAL DRUGS ON ITS HEALING
- EFFECTS OF ADRENERGIC BLOCKING AGENTS ON GASTRIC SECRETION AND STRESS-INDUCED GASTRIC ULCER IN RATS
- Synthesis and Structure-Activity Relationships of Substituted 2-[(2-Imidazolylsulfinyl)methyl]anilines as a New Class of Gastric H^+/K^+-ATPase Inhibitors. II
- SYNERGISM AND DRUG-RECEPTOR
- EFFECTS OF STRYCHNINE, DERIVATIVES OF PHENYL ACETATE AND CATECHOLAMINES ON CONTRACTION AND ACETYL CHOLINE OUTPUT FROM THE CHOLINERGIC NERVE ENDING OF GUINEA PIG ILEUM