喉頭と下咽頭の同時重複癌症例

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A case of squamous cell carcinoma occurring simultaneously in the larynx (T2NO) and hypopharynx (T2NO) was reported. A 64-year-old man complained of hoarseness without other symptoms. He was a heavy smoker (30 cigarettes a day) and also heavy drinker since youth.On the otolaryngological examinations, tumor of the left vocal cord with impaired movement was observed, and biopsy showed well differentiated squamous cell carcinoma.When the patient was operated, another tumor was observed, in the hypopharynx and pharyngolaryngectomy was performed. Pathological findings of the hypopharyngeal tumor showed also well differentiated squamous cell carcinoma. Supraglottic metaplasia was in the grade II by Pyronin Y staining method.Double cancers of the larynx and hypopharynx were found only in 4 cases including this case in the Japanese literature. Simultaneous primary cancers were seen in 2 cases.We had found multiple primary cancers in 7.0% of 63 cases of laryngeal cancers. Multicentric canceration was always controversial in laryngeal cancers.On the other hand, the patients with cancer in the hypopharynx have a high risk (12.7%) in vulnerability from cancer of the digestive system where dysplastic changes occur in the epithelial layer. Multifocal field carcinogenesis should be considered in hypopharyngeal cancers.So the importance of careful examination and long-term follow-up was emphasized in a case of rare tumors in the oro-respiratory system.
社団法人日本耳鼻咽喉科学会の論文

喉頭と下咽頭の同時重複癌症例

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