A 20-year Clinicopathological Study of Colorectal Cancer with Special Reference to Changing Surgical Treatment and Survival Rate.

概要

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From 1972 until 1991, 1089 patients with colorectal cancer underwent surgery at our institute. We divided the 20-year period into 5 -year terms and studied age distribution, tumor location and stage, operation method, resection rate and survival rate. The number of patients with colorectal cancer increased especially among males and the aged at the time of diagnosis during 20 years. Rectal tumors decreased while tumors located in the sigmoid colon increased significantly. Multiple colorectal cancers increased significantly over the 20 years, with synchronous multiple colorectal cancers being over 60 % of total multiple colorectal cancers. Patients with associated malignant tumors increased five times during the study period. Sphincter preserving methods and sigmoidectomy were increasingly employed. The cumulative 5 -year survival rate after curative surgical resection of single colorectal cancers was 73.8%, but the survival rate after curative anterior resection was 91.7 % in the last 5 years, a better rate than with Miles' operation.<BR>These results suggest that in order to increase the survival rate and enhance postoperative quality of life, the operative procedure must be chosen according to patients' characteristics.
日本大腸肛門病学会の論文