Clinicopathological features of "strictured colorectal cancer".

概要

論文の詳細を見る
A new trial is made of quantitative criteria with colorectal "string-stricture carcinoma". The strictured colorectal cancer is defined as follows; the tumor circum-ratio is more than 80% and transverse diameter of the tumor is less than 50% of distal neighboring intestinal circumference. Strictured type cancer patients consist of 5.6% (25 cases) of 446 primary cases surgica-lly treated in our institute during nine-year period from 1978 to 1986. This specific subtype of colorectal cancer is reviewed the clinicopathological aspects from the standpoint of treat-ment modality. The results obtained are as follows; 1) 24 patients (52%) presented with intestinal obstruction required emergency operation. 2) Strictured colorectal cancers show wide intramural spreading, marked vascular per-meation, depth of invasion, fibrous stromal reaction, but poor stromal inflammatory cellular infiltration. 3) This type of tumor has higher recurrent rate (43%) and relatively poor 5-year-sur-vival rate (38%), even if curative resection is performed. It is concluded that in addition to radical excision with wider lymphnode dissection, highly recommended are postoperative adjuvant therapy, i. e., chemotherapy, immunotherapy.