Brain Metastases of Malignant Melanoma Showing Unbalanced Whole Arm Chromosomal Translocations der (8; 14)(q10; q10) and der (11; 15)(q10; q10) in a Japanese Patient
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概要
- 論文の詳細を見る
Since malignant melanoma is a rare malignancy in Japan, little is known about the cytogenetic abnormalities in Japanese patients. We report a case of malignant melanoma showing complex chromosomal abnormalities. A 70-yearold woman was admitted to our hospital because of anorexia, delirium, and right hemiplegia. Cranial CT disclosed several metastatic brain tumors. Multiple subcutaneous and intra-abdominal metastases were also found. A diagnosis of metastatic malignant melanoma was made by biopsy of a subcutaneous tumor. Chromosomal analysis of the tumor cells disclosed complex karyotypic abnormalities including novel unbalanced whole arm translocations der (8; 14) (q10; q10) and der (11; 15) (q10; q10).(Internal Medicine 40: 956-960, 2001)
- 社団法人 日本内科学会の論文
著者
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Imai Kohzoh
札幌医科大学 生化学
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IMAI Kohzoh
Sapporo Medical University
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IMAI KOHZOH
The First Department of Internal Medicine, Sapporo Medical University School of Medicine
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Kazama Yoshi
天使病院
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SHIMIZU HARUO
First Department of Internal Medicine, Sapporo Medical University
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Shimoji Hideki
Department Of Gastroenterology Muroran General Hospital
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Takahashi T
The Second Department Of Internal Medicine Mie University School Of Medicine
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Yoshida Mio
First Department Of Internal Medicine Sapporo Medical University
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Imai Kohzoh
The First Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Shimizu Hiroyuki
Second Department Of Internal Medicine Tenshi Hospital
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TAKAHASHI Tohru
the Second Department of Internal Medicine, Tenshi Hospital
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KAZAMA Yoshie
the Second Department of Internal Medicine, Tenshi Hospital
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SHIMIZU Haruo
the Second Department of Internal Medicine, Tenshi Hospital
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YOSHIMOTO Mitsuru
the Second Department of Internal Medicine, Tenshi Hospital
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TSUJISAKI Masayuki
the Second Department of Internal Medicine, Tenshi Hospital
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KAZAMA Yoshie
Second Department of Internal Medicine, Tenshi Hospital
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Kazama Yoshie
Second Department Of Internal Medicine Tenshi Hospital
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Imai K
Department Of Internal Medicine Sapporo Medical University School Of Medicine
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Takahashi Toru
Department Of Hematology And Gastroenterology Caress Alliance Tenshi Hospital
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YOSHIMOTO Mitsuru
Department of Hematology and Gastroenterology, Caress Alliance Tenshi Hospital
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TSUJISAKI Masayuki
Department of Hematology and Gastroenterology, Caress Alliance Tenshi Hospital
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Tsujisaki Masayuki
Department Of Hematology And Gastroenterology Caress Alliance Tenshi Hospital
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Shimizu Haruo
Department Of Gastroenterology Muroran General Hospital
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