Expression of an Immunotherapeutic Target Antigen 17-1A for Colorectal Cancer in Multiple Myeloma

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概要

• 論文の詳細を見る

• A colorectal cancer-associated 17-1A antigen is an effective therapeutic target with monoclonal antibody (mAb) for preventing the recurrence of colorectal cancer. We evaluated its expression in myeloma cell lines and bone marrow cells from patients with multiple myeloma or primary macroglobulinemia by indirect immunofluorescence assays. Antigen 17-1A was shown positive in 3 out of 4 cell lines tested and in 8 out of 9 bone marrow cell specimens including 6 multiple myelomas, one IgG-producing chronic lymphoproliferation and 2 primary macroglobulinemias. These data suggest that adminisration of mAb 17-1A may be a new feasible immunotherapy to those indolent, but incurable diseases.

• Yamaguchi University Graduate School of Medicineの論文

著者

• Imai K

  Sapporo Medical University

• Imai Kohzoh

  札幌医科大学 生化学

• Imai Kohzoh

  鹿児島大学 医歯学総合研究科病理学第2

• Hayashi Toshiaki

  First Department Of Internal Medicine Sapporo Medical University

• ADACHI Masaaki

  First Department of Internal Medicine, Sapporo Medical University

• Takahashi H

  First Department Of Internal Medicine Sapporo Medical University

• Adachi M

  First Department Of Internal Medicine Sapporo Medical University

• Adachi Masaaki

  札幌医科大学 第1内科

• Hinoda Y

  First Department Of Internal Medicine Sapporo Medical University

• Imai Kohzoh

  Department Of Internal Medicine (section 1) Sapporo Medical University School Of Medicine

• TAKAHASHI Tohru

  Tenshi Hospital

• Hayashi T

  First Department Of Internal Medicine Sapporo Medical University

• Hayashi Toshiaki

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Hinoda Yuji

  Department Of Clinical Labolatory Medicine Yamaguchi University School Of Medicine

• Hinoda Y

  Sapporo Medical Univ. Sapporo Jpn

• Takahashi Tohru

  First Department Of Internal Medicine Sapporo Medical University

• Tsukuda Hiroyuki

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Tsukuda Hiroyuki

  Department Of Internal Medicine (section 1) Sapporo Medical University School Of Medicine

• Adachi Masaaki

  First Department Of Internal Medicine Sapporo Medical University

• Takahashi Hiroki

  First Department Of Internal Medicine Sapporo Medical University

• Takahashi Takeshi

  First Department Of Internal Medicine Sapporo Medical University

• Adachi Masaaki

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Tsukuda Hiroyuki

  First Department Of Internal Medicine Sapporo Medical University

• Takahashi Hiroki

  札幌医科大学 第1内科

• Takahashi Tohru

  Department Of Pathology Institute Of Development Aging And Cancer Tohoku University

• Takagi Hideyasu

  札幌医科大学 内科学第一

• Hayashi T

  Dohto Hospital Sapporo Jpn

• Yajima Hidetaka

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

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