Syndrome of inappropriate secretion of antidiuretic hormone induced by tacrolimus hydrate <Case Report>

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概要

• 論文の詳細を見る

• A 24-year-old man with chronic myelocytic leukemia underwent a bone marrow transplant. Tacrolimus hydrate (FK506) was given for the prophylaxis of graft versus host disease (GVHD), but subsequently grade II skin and intestinal GVHD occurred. Increased administration of FK506 with simultaneous use of prednisolone relieved GVHD; however, hyponatremia occurred. Because renal function was normal and urinary osmolality was higher than serum osmolality, syndrome of inappropriate secretion of antidiuretic hormone (SIADH) was diagnosed. When FK506 was replaced by cyclosporine on day 43, the hyponatremia improved rapidly. FK506 is thought to be the agent that caused SIADH in the present case.

• 札幌医科大学の論文

著者

• IMAI Kohzoh

  First Department of Internal Medicine, Sapporo Medical University

• Imai K

  Sapporo Medical University

• Imai Kohzoh

  札幌医科大学 生化学

• Imai Kohzoh

  鹿児島大学 医歯学総合研究科病理学第2

• Hayashi Toshiaki

  First Department Of Internal Medicine Sapporo Medical University

• ISHIDA Tadao

  First Department of Internal Medicine, Sapporo Medical University

• Imai Kohzoh

  Department Of Internal Medicine (section 1) Sapporo Medical University School Of Medicine

• Imai Kohzoh

  First Department Of Internal Medicine Sapporo Medical University

• OBATA TOSHIRO

  First Department of Internal Medicine, Cancer Research Institute, Sapporo Medical University

• Ishida Tadao

  First Department Of Internal Medicine Sapporo Medical University

• Hayashi Toshiaki

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• IKEDA Hiroshi

  First Department of Pathology, School of Medicine, Aichi Medical University

• Nishimura Susumu

  First Department of Internal Medicine, Sapporo Medical University School of Medicine

• Maemori Masayo

  Department of Hematology, Teine Keijinkai Hospital

• Tsukuda Hiroyuki

  First Department of Internal Medicine, Sapporo Medical University School of Medicine

• Maemori Masayo

  Department Of Hematology Teine Keijinkai Hospital

• Tsukuda Hiroyuki

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Tsukuda Hiroyuki

  Department Of Internal Medicine (section 1) Sapporo Medical University School Of Medicine

• Obata Toshiro

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Obata Toshiro

  First Department Of Internal Medicine Cancer Research Institute Sapporo Medical University

• Tsukuda Hiroyuki

  First Department Of Internal Medicine Sapporo Medical University

• Nishimura Susumu

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

• Takahashi Hiroki

  札幌医科大学 第1内科

• Takagi Hideyasu

  札幌医科大学 内科学第一

• Hayashi T

  Dohto Hospital Sapporo Jpn

• Ikeda Hiroshi

  First Department Of Internal Medicine Sapporo Medical University School Of Medicine

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