Visualization of the Heart and Determination of Left Ventricular Mass in Rats by Echocardiography.

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概要

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• A high-frequency transducer was used to determine the optimal parameters for visualizing the heart in 40 normal Wistar, 15 SHR, and 10 aorta-banded rats. The rats were 5 to 30 weeks old and weighed between 105 and 705 grams. Two-dimensional and M-mode views of the ventricles, atria, valves, and great arteries were obtained by placing the transducer beneath the rats through the left or right parasternal window in either the prone or the right decubitus positions, respectively. Left ventricular (LV) mass was determined on the basis of a spheroid model; these values correlated well with the LV weight for both the Wistar rats (r=0.94, p<0.001) and the rats with cardiac hypertrophy due to pressure load (r=0.87, p<0.001). These results were highly reproducible. This indicates that echocardiography is useful for obtaining quantitative measurements in rats.

• International Heart Journal刊行会の論文

著者

• Shimoo Kazutoshi

  Second department of medicine, Kyoto Prefectural University of Medicine

• Nakamura Takashi

  Second Department Of Internal Medicine Kyoto Prefectural University Of Medicine

• Shima Masami

  Second Department of MedicineKyoto Prefectural University of Medicine

• Kuribayashi Toshiro

  Second Department Of Anatomy Kyoto Prefectural University Of Medicine

• Nakagawa Masao

  Second Department Of Internal Medicine Kyoto Prefectural Medical College

• KATSUME Hiroshi

  Second Department of Internal Medicine, Kyoto Prefectural University of Medicine

• MATSUBARA Kin-ya

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

• MATSUMURO Akiyoshi

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

• KATSUME Hiroshi

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

• AZUMA Akihiro

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

• Shima Masami

  Second Department of Anatomy, Kyoto Prefectural University of Medicine

• SHIMOO Kazutoshi

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

• NAKAGAWA Masao

  Second Department of Medicine and, Kyoto Prefectural University of Medicine

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