Tissue Edema and Arterial Lesions Produced by Pure Submaxillary Gland Renin of Mouse
スポンサーリンク
概要
- 論文の詳細を見る
In order to identify the nature of the substance(s) that causes pancreatic edema, pleural effusion, hematocrit increase, and vascular lesion upon administration of renal extracts, effects of a pure preparation of submaxillary gland renin of mouse on blood vessels were studied. This enzyme was administered intraperitoneally to conscious anehpric rats. Blood pressure elevation recorded under unrestricted conditions was proportional to pancreatic edema, pleural effusion, hematolcrit increase, and vascular lesions in small arteries and arterioles. Since the renin administered does not contain any substances and since the function of this enzyme is quite analogous to renal renin, these results have been interpreted to indicate that renin possesses both pressor and permeability activities and that the action of renin alone can account for the vascular lesions and the increased vascular permeability.
- International Heart Journal刊行会の論文
著者
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ONOYAMA Kaoru
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University
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Omae Teruo
Second Department Of Internal Medicine Faculaty Of Medicine Kyushu University
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Inagami Tadashi
Department Of Biochemistry And Hypertension Center School Of Medicine Vanderbilt University
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Onoyama Kaoru
Second Department Of Internal Medicine Faculty Of Medicine Kyushu University
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ONOYAMA Kaoru
Second Department of Internal Medicine and Department of Anatomy, Faculty of Medicine, Kyushu University
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Omae Teruo
Second Departemnt of Internal Medicine, Kyushu University
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