Long-term Clinical Effect of Calcium Inhibitors in Hypertrophic Cardiomyopathy Compared to the Effect of Beta-blocking Agents : A Preliminary Report with Special Reference to the Beneficial Effect of Nifedipine on Angina Pectoris
スポンサーリンク
概要
- 論文の詳細を見る
Long-term clinical effects of beta-blockers (propranolol in most cases) and calcium inhibitors (nifedipine in most cases) were studied in 16 patients with hypertrophic cardiomyopathy.On overall subjective symptoms, beta-blockers were effective in 50% of symptomatic patients, while calcium inhibitors were effective in only 33%. On angina pectoris, however, calcium inhibitors were superior to beta-blockers in our patients. Blood pressure decreased with each drug, and the decrease was significant with nifedipine. Otherwise there was no change in physical findings with either drug.Long-term (more than 6 months) use of beta-blockers resulted in an increase in cardiothoracic ratio on chest X-ray, a decrease in left ventricular ejection fraction on echocardiogram and more pronounced ST-T change on electrocardiogram. Prolonged use of nifedipine resulted in a slight decrease in cardiothoracic ratio, but no systematic change on echocardiogram and on electrocardiogram.
- International Heart Journal刊行会の論文
著者
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Iizuka Masahiko
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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UCHIDA Yasumi
Second Department of Internal Medicine,University of Tokyo
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Kato Akihito
Second Department of Internal Medicine Tokyo University School of medicine
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Takabatake Yutaka
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Koide Tadashi
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Ozeki Katsuhiko
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Koide Tadashi
The Second Department T Of Internal Medicine Faculty Of Medicine University Of Tokyo
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Koide Tadashi
2nd Dept. Of Internal Medicine Fac. Of Medicine Univ. Of Tokyo
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Koide Tadashi
The Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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MOROOKA Shigenori
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Koide Tadashi
The 2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo Tokyo
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TANAKA Shugo
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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KAKIHANA Masaaki
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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OYA Tetsuo
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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MOMOMURA Shinichi
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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MURAO Statoru
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
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Uchida Yasumi
Second Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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KOIDE Tadashi
Second Department of Internal Medicine, Faculty of Medicine University of Tokyo
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OZEKI Katsuhiko
Second Department of Internal Medicine, Faculty of Medicine University of Tokyo
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TAKABATAKE Yutaka
Second Department of Internal Medicine, Faculty of Medicine University of Tokyo
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