育成豚における飼料添加物サリノマイシンの効果

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Salinomycin is a polyether antibiotic prepared from a fermented broth of a strain of Streptomyces albus. In order to investigate the growth promoting effects of salinomycin, fifteen trials were conducted at four experimental stations located in Yamagata, Ishikawa, Tottori and Shimane Prefectures, Japan. Four hundred and thirty weaning pigs were fed a complete ration with salinomycin at levels of 0, 25, 50 and 100ppm, during weaning (4 weeks) and growing (8 weeks) periods. Body weight gains in the pigs were increased by addition of salinomycin by 13 to 15% (P<0.05) during the growing period, and by 11 to 13% over the whole experimental period. There were significant relationships between salinomycin level and body weight gain (growing period: y=-0.00106x2+0.151x+32.94, R2=0.700, P<0.01, xoptimum=71ppm, whole experimental period; y=0.00136x2+0.181x+42.73, R2=0.734, P<0.01, xoptimum=67ppm). Feed intakes were slightly increased in salinomycin treated groups relative to the control group. Consequently, feed conversion ratios were improved by addition of salinomycin by 6 to 8% (P<0.05) during the growing period and by 6 to 7% (P<0.05) over the whole experimental period. Significant secondary dose-response relationships were found between salinomycin level and feed conversion ratio (growing period; y=0.000036x2-0.00555x+2.693, R2=0.732, P<0.01, xopitmum=77ppm, whole experimental period; y=0.000038x2-0.00547x+2.556, R2=0.795, P<0.01, xoptimum=72ppm). Based on these results, it is reasonable to assume that the addition of salinomycin at levels of 50-80ppm is the most effective for growth promotion in pigs.
社団法人日本畜産学会の論文

育成豚における飼料添加物サリノマイシンの効果

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