概日リズムの生理機構 : 複数振動体系
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Possibilities that multiple circadian oscillators coexist within one individual organism are reviewed. The possibility has been suggested in two ways. One is cut-and-see experiments, in which the lesion of the putative structure in the central nervous system containing the driving oscillator has not always led to comlplete disappearance of the overt rhythm. The other is kinetic or functional analyses which resulted in finding of desynchronization, rhythm-splitting and some other phenomena suggestive of the existence of multiple oscillators. Under present circumstances, the concrete feature of hierarchy supposed to be made up of the oscillators is quite unknown, although some speculations for it have been presented. Methodological apd technical problems pertaining to the rhythm study are also discussed.
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