Spontaneous Fibrosarcoma with Pleomorphic Appearance in an Aged Brown Norway Rat
スポンサーリンク
概要
- 論文の詳細を見る
An 18-month-old male Brown Norway (BN) rat showed a grayish-white subcutaneous mass in the right cheek. Histologically, the mass was composed of highly pleomorphic cells producing collagen. Immunohistochemical analysis showed that the tumor cells were strongly positive for vimentin and partially positive for Ki-67; however, they were negative for ED-1, ED-2, S-100, cytokeratin, desmin and myoglobin. Ultrastructurally, the cytoplasms of the tumor cells contained well-developed rough endoplasmic reticulum. Thus, the tumor had no characteristic feature other than collagen production and was diagnosed as a fibrosarcoma.
- 日本毒性病理学会の論文
著者
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Funabashi Hitoshi
Safety Research Laboratories, Dainippon Sumitomo Pharma. Co., Ltd.
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Seki Takaki
Safety Research Laboratories, Dainippon Sumitomo Pharma. Co., Ltd.
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Michimae Yoshiko
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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Toyosawa Kaoru
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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Matsumoto Izumi
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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Kouchi Mami
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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Koujitani Takatoshi
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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Kouchi Mami
Safety Research Laboratories Dainippon Pharmaceutical Co. Ltd.
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Seki Takaki
Safety Res. Laboratories Dainippon Sumitomo Pharma Co. Ltd.
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Toyosawa K
大日本住友製薬安全性研究所
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Toyosawa Kaoru
Safety Research Laboratories Dainippon Sumitomo Pharma Co. Ltd.
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Funabashi Hitoshi
Safety Research Laboratories Dainippon Sumitomo Pharma Co. Ltd.
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Tochitani Tomoaki
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
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