Spontaneous Fibrosarcoma with Pleomorphic Appearance in an Aged Brown Norway Rat
スポンサーリンク
概要
- 論文の詳細を見る
An 18-month-old male Brown Norway (BN) rat showed a grayish-white subcutaneous mass in the right cheek. Histologically, the mass was composed of highly pleomorphic cells producing collagen. Immunohistochemical analysis showed that the tumor cells were strongly positive for vimentin and partially positive for Ki-67; however, they were negative for ED-1, ED-2, S-100, cytokeratin, desmin and myoglobin. Ultrastructurally, the cytoplasms of the tumor cells contained well-developed rough endoplasmic reticulum. Thus, the tumor had no characteristic feature other than collagen production and was diagnosed as a fibrosarcoma.
- 2010-12-01
著者
-
Koujitani Takatoshi
大日本住友製薬安全性研究所
-
Koujitani Takatoshi
Department Of Toxicology And Teratology Developmental Research Laboratories Dainippon Pharmaceutical
-
Michimae Yoshiko
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
-
Toyosawa Kaoru
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
-
Matsumoto Izumi
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
-
Koujitani Takatoshi
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
-
Tanaka K
Department Of Gastroenterological Surgery Yokohama City University Graduate School Of Medicine
-
Kouchi Mami
大日本住友製薬安全性研究所
-
Kouchi Mami
Safety Research Laboratories Dainippon Pharmaceutical Co. Ltd.
-
Seki Takaki
Safety Res. Laboratories Dainippon Sumitomo Pharma Co. Ltd.
-
Toyosawa K
大日本住友製薬安全性研究所
-
Toyosawa Kaoru
Safety Research Laboratories Dainippon Sumitomo Pharma Co. Ltd.
-
Funabashi Hitoshi
Safety Research Laboratories Dainippon Sumitomo Pharma Co. Ltd.
-
Tochitani Tomoaki
Safety Research Laboratories, Dainippon Sumitomo Pharma Co., Ltd.
-
Tanaka Kouji
Department Of Gastrointestinal And Pediatric Surgery Mie University Graduate School Of Medicine
-
Matsumoto Izumi
Safety Research Laboratories Dainippon Sumitomo Pharma Co. Ltd.
関連論文
- The First Case of Feline Infectious Peritonitis-like Pyogranuloma in a Ferret Infected by Coronavirus in Japan
- A Novel "Nihon" Rat Model of a Mendelian Dominantly Inherited Renal Cell Carcinoma
- Influences of biofluid sample collection and handling procedures on GC-MS based metabolomic studies(METHODS)
- Canine SPECT studies for cerebral amino acid transport by means of ^I-3-iodo-α-methyl-L-tyrosine and preliminary kinetic analysis
- Long-Term Treatment With Ranirestat (AS-3201), a Potent Aldose Reductase Inhibitor, Suppresses Diabetic Neuropathy and Cataract Formation in Rats
- Contrast-enhanced sonography of pancreatic carcinoma : correlations with pathological findings
- Improvement of the embryonic stem cell test endpoint analysis by use of field potential detection
- Giant mesenchymal hamartoma of the liver in an adult
- Spleen-Preserving Distal Pancreatectomy Combined with Distal Gastrectomy for Distal Pancreatic Lesion and Gastric Cancer : Report of a Case
- Porcelain gallbladder complicated with pancreas divisum
- Primary malignant peripheral nerve-sheath tumor of the common bile duct
- Long-term survival in a patient with hepatocellular carcinoma with resection of a metastatic lymph node after percutaneous ethanol injection therapy
- Risk factors of posthepatectomy liver failure after portal vein embolization
- Indications for curative resection of advanced gallbladder cancer with hepatoduodenal ligament invasion
- Adjuvant therapies using biliary stenting for malignant biliary obstruction
- Micrometastatic Colorectal Cancer Lesions in the Liver
- A Novel Renal Carcinoma Predisposing Gene of the Nihon Rat Maps on Chromosome 10
- Tandem Repeats of Lactoferrin-Derived Anti-Hepatitis C Virus Peptide Enhance Antiviral Activity in Cultured Human Hepatocytes
- Mitotic Checkpoint Protein hsMAD2 as a Marker Predicting Liver Metastasis of Human Gastric Cancers
- Application of Prohibitin Immunohistochemistry to Rat Livers Treated with Methapyrilene Hydrochloride
- Mucinous Adenocarcinoma of the Jejunum in a F344 Rat
- Assessment of T cell dependent antibody response, hematology, pathology and immunophenotyping in the identical rat on immunotoxicology studies : Immunotoxicology study with Cyclophosphamide(Proceedings of the 32nd Annual Meeting)
- Expression of Vascular Endothelial Growth Factor (VEGF) Family Members in Breast Cancer
- Relationship between liver weight change and gene expression of hepatic cytochrome P450 isoforms in clobazam-treated rats(Proceedings of the 32nd Annual Meeting)
- Usefulness of field potential as a marker of embryonic stem cell-derived cardiomyocytes, and endpoint analysis of embryonic stem cell test
- Roles of Extracellular Signal-regulated Kinase 1/2 and p38 Mitogen-activated Protein Kinase in the Signal Transduction of Basic Fibroblast Growth Factor in Endothelial Cells during Angiogenesis
- Clotrimazole, an Imidazole Antimycotic, Is a Potent Inhibitor of Angiogenesis
- Simultaneous Bindings of uPA and Latent TGF-β for the Activation of Latent TGF-β in Homotypic Smooth Muscle Cells
- Intravital imaging of DSS-induced cecal mucosal damage in GFP-transgenic mice using two-photon microscopy
- Perioperative Host-Tumor Inflammatory Interactions : A Potential Trigger for Disease Recurrence Following a Curative Resection for Colorectal Cancer
- Ultrasonically Activated Shears in Gastrectomy for Large Gastric Cancers
- Operative Morbidity Associated with Groin Dissections
- Spontaneous Fibrosarcoma with Pleomorphic Appearance in an Aged Brown Norway Rat
- Liver transplantation for primary sclerosing cholangitis
- Minimum sizes for remnant and transplanted livers in rats
- Application of Prohibitin Immunohistochemistry to Rat Livers Treated with Methapyrilene Hydrochloride
- Swallowing Disorder and Inhibition of Cough Reflex Induced by Atropine Sulfate in Conscious Dogs
- DPEP1, expressed in the early stages of colon carcinogenesis, affects cancer cell invasiveness
- Multiple Solitary Leiomyomas in the Esophagus : Report of a Case
- Immunohistochemical and Ultrastructural Analyses of Cytoplasmic Blood Plasma Inclusions of Rat Hepatocytes
- Evaluation of ovarian toxicity of sodium valproate (VPA) using cultured rat ovarian follicles
- Evaluation of ovarian toxicity of mono-(2-ethylhexyl) phthalate (MEHP) using cultured rat ovarian follicles
- Severe outflow block syndrome caused by compression by the swollen caudate lobe after living donor liver transplantation : report of a case
- Right hepatectomy with resection of caudate lobe and extrahepatic bile duct for hilar cholangiocarcinoma
- Prognostic significance of glucose transporter-1 (GLUT1) gene expression in rectal cancer after preoperative chemoradiotherapy
- Emergency versus elective living-donor liver transplantation : a comparison of a single center analysis
- Cystic Cholangioma in the Thoracic Cavity of a Rat
- The First Case of Feline Infectious Peritonitis-like Pyogranuloma in a Ferret Infected by Coronavirus in Japan
- High TrkB expression levels are associated with poor prognosis and EMT induction in colorectal cancer cells
- Spontaneous Fibrosarcoma with Pleomorphic Appearance in an Aged Brown Norway Rat
- Immunohistochemical and Ultrastructural Analyses of Cytoplasmic Blood Plasma Inclusions of Rat Hepatocytes
- Immunohistochemical and Ultrastructural Analyses of Cytoplasmic Blood Plasma Inclusions of Rat Hepatocytes