Acute Phase Response in Naturally Occurring Coliform Mastitis.
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概要
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Changes in the activities of serum cytokines and in acute phase response were observed in dairy cows with naturally occurring coliform mastitis. Seven cows with severe mastitis showed systemic and mammary inflammatory response throughout the observation period, and 11 cows with mild mastitis recovered and were able to be milked within 3 days of onset of mastitis. Serum interleukin (IL)-1 and tumor necrosis factor (TNF) activities were higher in the severe group than in the mild group at the first appearance of symptoms. Elevated IL-1 activity was evident in the severe group throughout the observation period. Serum α-1-acidglycoprotein (α1AG) concentration began to rise with the beginning of mastitis in the severe group, and peaked at 9 days. Serum haptoglobin (Hp) concentrations peaked at 3 days, and decreased gradually after 3 days in the severe group. These results showed that there are dynamic changes in serum IL-1 activity and in serum α1AG and Hp concentrations in cows with severe coliform mastitis.
- 公益社団法人 日本獣医学会の論文
著者
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Ohtsuka Hiromichi
Department Of Veterinary Internal Medicine School Of Veterinary Medicine And Animal Sciences Kitasat
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Hoshi Fumio
Department Of Small Animal Internal Medicine School Of Veterinary Medicine Kitasato University
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Tamura Keiji
Saikin Kagaku Institute
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OHTSUKA Hiromichi
Department of Veterinary Internal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University
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KUDO Katsunori
Ishikari Agricultural Mutual Relief Association
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MORI Kazunori
Ikari Kogen Farm
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NAGAI Fuminori
Ishikari Agricultural Mutual Relief Association
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HATSUGAYA Atsushi
Iburi Agricultural Mutual Relief Association
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TAJIMA Motoshi
School of Veterinary Medicine, Hokkaido University
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KOIWA Masateru
Veterinary Teaching Hospital, School of Veterinary Medicine, Rakuno Gakuen University
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KAWAMURA Sei-ichi
Department of Veterinary Internal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University
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Hoshi Fumio
Department of Veterinary Internal Medicine, School of Veterinary Medicine and Animal Sciences, Kitasato University
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