Factors Influencing Measurement of Serum Iron Concentration in Dogs: Diurnal Variation and Hyperferritinemia
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概要
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We evaluated diurnal variation and hyperferritinemia as factors that influence the values of serum iron concentration in dogs, using the International Committee for Standardization in Hematology (ICSH) colorimetric method. Serum iron levels were significantly higher in the morning than in the evening in 6 clinically healthy beagle dogs, and the maximum decrease in serum iron concentration was 47.3%. Moreover, the change in serum iron concentrations in 22 clinical canine cases with various serum ferritin levels were evaluated by immunoprecipitation of ferritin. The rate of decline in the serum iron concentrations positively correlated with serum ferritin levels (r=0.48, P=0.024). These results show that it is necessary to consider the sampling time and serum ferritin level for accurate interpretation of serum iron concentrations in dogs.
著者
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Kanai Kazutaka
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University
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Hoshi Fumio
Department Of Small Animal Internal Medicine School Of Veterinary Medicine Kitasato University
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HIGUCHI Seiichi
Department of Food Science and Technology, Faculty of Agriculture, Kyushu University
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Orino Koichi
Laboratory Of Veterinary Biochemistry School Of Veterinary Medicine Kitasato University
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Watanabe Kiyotaka
Laboratory Of Veterinary Biochemistry School Of Veterinary Medicine Kitasato University
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Hori Yasutomo
Department Of Internal Medicine School Of Veterinary Medicine & Animal Science Kitasato Universi
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Ito Naoyuki
Department Of Chemistry Keio University
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HIGUCHI Seiichi
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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CHIKAZAWA Seishiro
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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CHIKAZAWA Seishiro
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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ORINO Koichi
Laboratory of Biochemistry, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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HOSHI Fumio
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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KANAI Kazutaka
Department of Small Animal Internal Medicine, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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Ito Naoyuki
Department of Chemical Engineering, Tokyo Institute of Technology
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WATANABE Kiyotaka
Laboratory of Biochemistry, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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WATANABE Kiyotaka
Laboratory of Biochemistry, School of Veterinary Medicine, Kitasato University, 23–35–1 Higashi, Towada, Aomori 034–8628, Japan
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