C57BL/6 Mice Infected with Neospora caninum During Administration of Progesterone Show Bias Toward Type 2 Immune Response
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概要
- 論文の詳細を見る
To clarify the role of progesterone in the development of immune responses during pregnancy against Neospora caninum infection, C57BL/6 mice were given a progesterone pellet, and measured on Interferon-γ and interleukin-4 production following the infection. IFN-γ production in the prescribed group was significantly lower than that in the intact group on day 40 post administration. IL-4 producing cell population in the prescribed group was larger than that in the intact group. These results suggest that progesterone may alter the balance of cytokine production, and that the bias toward type 2 immune response may remain for a certain period after the infection.
著者
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MAEDA Ryuichiro
Department of Basic Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
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Kano Rika
Department Of Disease Control Graduate School Of Veterinary Medicine Hokkaido University
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KOBAYASHI Yoshiyasu
Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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OMATA Yoshitaka
Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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OMATA Yoshitaka
Department of Basic Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine
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KUDO Akimasa
Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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KAMIYA Hikaru
Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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KANO Rika
Department of Basic Veterinary Science, School of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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