Peripheral Nerve Lesions in a Case of Equine Motor Neuron Disease
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概要
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A male 14-year-old Arab horse was pathologically diagnosed as equine motor neuron disease (EMND), which was kept as a breeding horse on a farm in Tokachi district of Hokkaido in Japan. On examination of the peripheral nerves, the most characteristic feature was Wallerian-type degeneration revealed by myelinoclasis associated with myelin ovoids which were sometimes infiltrated by macrophages. The other abnormalities were axonal swellings which were surrounded by thin myelin sheaths. Ultrastructurally, the axonal swelling was due to an accumulation of neurofilaments, and was accompanied by a thin and degenerating myelin sheaths. In teased nerve fiber preparations, the most conspicuous change was myelinoclasis represented by segmentation into myelin ovoids or balls. Occasionally, segmental demyelination and axonal degeneration characterized by multifocal axonal swelling were observed.
- 社団法人 日本獣医学会の論文
著者
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Furuoka Hidefumi
Department Of Basic Veterinary Medicine Obihiro University Of Agriculture And Veterinary Medicine
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Matsui Takane
Department Of Clinical Veterinary Science Obihiro University Of Agriculture And Veterinary Medicine
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KOBAYASHI Yoshiyasu
Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
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Matsui Takane
Department of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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Hasegawa Mituru
Department of Veterinary Pathology, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan
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