Acute Hepatitis due to Hepatitis E Virus Genotype 1 As an Imported Infectious Disease in Japan
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概要
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An 18-year-old Nepalese man was admitted due to general malaise and anorexia a month after coming to Japan. Laboratory tests showed elevation of transaminase and positivity for IgM anti-HEV antibody. Serum HEV RNA was detected by RT-PCR amplifications. An HEV genome phylogenetic tree, constructed using an 821-nucleotide sequence in the open reading frame 1, indicated that the genotype was 1. HEV genotype 1 is epidemic in South Asia, Africa and South America, and the incidence of acute hepatitis due to HEV genotype 1 is low in Japan. Thereafter, attention should be paid to HEV genotype 1 infection as an imported infectious disease.
著者
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Ikeda Fusao
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Kang Jong-hon
Center For Gastroenterology Teine Keijinkai Hospital
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Takaki Akinobu
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Kobashi Haruhiko
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Yasunaka Tetsuya
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Miyake Yasuhiro
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Arai Masahiro
Department Of Mechanical Engineering And Science Tokyo Institute Of Technology
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Yamamoto Kazuhide
Department Of Electrical Engineering Nagaoka University Of Technology
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Takahashi Kazuaki
Department Of Animal Science Faculty Of Agriculture Tohoku University
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Iwasaki Yoshiaki
Department Of Diagnostic Pathology Graduate School Of Medicine The University Of Tokyo
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Iwasaki Yoshiaki
Department of Gastroenterology & Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
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Miyahara Koji
Department of Gastroenterology & Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
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