Long-term Combined Therapy with Very-low-dose Peginterferon and Ursodeoxycholic Acid Decreased the Spleen Size in a Patient with Hepatitis C Virus-related Cirrhosis
スポンサーリンク
概要
- 論文の詳細を見る
A 42-year-old woman with hepatitis C virus-related cirrhosis underwent peginterferon alpha-2b therapy combined with ribavirin but could not achieve a sustained viral response. Following discontinuation of this combined therapy, the patient's serum transaminase levels suddenly became elevated. Therefore, the administration of very-low-dose peginterferon alpha-2a with ursodeoxycholic acid was introduced. Thereafter, the patient's serum transaminase levels gradually improved. Four years later, enhanced computed tomography showed shrinkage of the spleen and enlargement of the liver. Long-term combined therapy with very-low-dose peginterferon and ursodeoxycholic acid may be effective not only in preventing disease progression, but also in improving portal hypertension in patients hepatitis C virus-related cirrhosis.
- 社団法人 日本内科学会の論文
著者
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Ando Masaharu
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Hirohata Mamoru
Department Of Internal Medicine Mitoyo General Hospital
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Miyake Yasuhiro
Department Of Gastroenterology & Hepatology Okayama University Graduate School Of Medicine Denti
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Asagi Akinori
Department Of Digestive Tract Internal Medicine Shikoku Cancer Center
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Nakatsu Morihito
Department Of Internal Medicine Mitoyo General Hospital
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Miyatake Hirokazu
Department Of Gastroenterology And Hepatology Okayama University Graduate School Of Medicine Dentist
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Anzai Taiko
Department of Internal Medicine, Mitoyo General Hospital, Japan
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Yasuhara Hisae
Department of Internal Medicine, Mitoyo General Hospital, Japan
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Moriya Akio
Department of Internal Medicine, Mitoyo General Hospital, Japan
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