Biological Activities of Korean Citrus obovoides and Citrus natsudaidai Essential Oils against Acne-Inducing Bacteria
スポンサーリンク
概要
- 論文の詳細を見る
This study was designed to analyze the chemical composition of Citrus obovoides (Geumgamja) and Citrus natsudaidai (Cheonyahagyul) oils and to test their biological activities. These citrus essential oils were obtained by steam distillation of fruits collected from Jeju Island, Korea, and were analyzed using gas chromatograph (GC)-flame ionization detectors (FID) and GC-MS. Limonene and γ-terpinene were the major components of the two citrus species. To evaluate in vitro anti-acne activity, they were tested against Propionibacterium acnes and Staphylococcus epidermidis, which are involved in acne. The Geumgamja and Cheonyahagyul oils exhibited antibacterial activity against both P. acnes and S. epidermidis. Their effects on DPPH radical scavenging, superoxide anion radical scavenging, and nitric oxide radical were also assessed. Cheonyahagyul and Geumgamja exhibited only superoxide anion radical-scavenging activity. To assess their potential usefulness in future cosmetic product applications, the cytotoxic effects of the two oils were determined by colorimetric MTT assays using two animal cell lines: normal human fibroblasts and HaCaT cells. They exhibited low cytotoxicity at 0.1 μl/ml in both cell lines. In addition, they reduced P. acnes-induced secretion of interleukin-8 (IL-8) and tumor necrosis factor alpha (TNF-α) in THP-1 cells, an indication of anti-inflammatory effects. Therefore, based on these results, we suggest that Geumgamja and Cheonyahagyul essential oils are attractive acne-mitigating candidates for topical application.
著者
-
LEE Nam
Department of Chemistry, Korea Military Academy
-
Yoon Weon-Jong
Research Group for Cosmetic Materials, Jeju Biodiversity Research Institute (JBRI), Jeju High-Tech D
-
Hyun Chang-Gu
Research Group for Cosmetic Materials, Jeju Biodiversity Research Institute (JBRI), Jeju High-Tech D
-
KIM Sang-Suk
Department of Chemistry, Cheju National University
-
BAIK Jong
Department of Chemistry, Cheju National University
-
OH Tae-Heon
Department of Chemistry, Cheju National University
関連論文
- Actinomycin D Identified as an Inhibitor of Discoidin Domain Receptor 2 Interaction with Collagen through an Insect Cell Based Screening of a Drug Compound Library(Pharmacology)
- 1,2,3,4,6-Penta-O-galloyl-β-D-glucose Protects Splenocytes against Radiation-Induced Apoptosis in Murine Splenocytes
- Isolation and characterization of a novel analyte from Bacillus subtilis SC-8 antagonistic to Bacillus cereus(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Antimutagenicity and Cytotoxicity of the Constituents from the Aerial Parts of Rumex acetosa(Pharmacognosy)
- Protective Effect of Triphlorethol-A from Ecklonia cava against Ionizing Radiation in vitro
- IS-020 Prenatal Diagnostic Clues for Fetus-in-fetu(the 44th Annual Meeting of Japanese Society of Pediatric Surgeons)
- Characterization of Lactobacillus spp. isolated from the feces of breast-feeding piglets(MICROBIAL PHYSIOLOGY AND BIOTECHNOLOGY)
- Effect of Palmitoleic Acid on Melanogenic Protein Expression in Murine B16 Melanoma
- Oenothera laciniata inhibits lipopolysaccharide induced production of nitric oxide, prostaglandin E_2, and proinflammatory cytokines in RAW264.7 macrophages(PLANT BIOTECHNOLOGY)
- A Case of Pre-Sezary Syndrome Preceded by Hand Lesions
- Poisson Equations with Nonlinear Source Terms on Networks
- Depigmentation of Melanocytes by (2Z,8Z)-Matricaria Acid Methyl Ester Isolated from Erigeron breviscapus
- Tepidimonas arfidensis Sp. Nov., a Novel Gram-Negative and Thermophilic Bacterium Isolated from the Bone Marrow of a Patient with Leukemia in Korea
- Biological Activities of Korean Citrus obovoides and Citrus natsudaidai Essential Oils against Acne-Inducing Bacteria
- Chemical Composition and Anti-inflammatory Effects of Essential Oil from Farfugium japonicum Flower
- Biological Activities of Korean Citrus obovoides and Citrus natsudaidai Essential Oils against Acne-Inducing Bacteria