New Anti-inflammatory 4-Hydroxyisoflavans from Solanum lyratum

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概要

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• Three new 4-hydroxyisoflavans, named lyratin A (1), lyratin B (2) and lyratin C (3), along with a known compound, 4,7,2′trihydroxy-4′-methoxyisoflavan (4), were isolated from the whole plant of Solanum lyratum. Their structures were established by means of detailed physical data analyses. In vitro, four compounds showed anti-inflammatory activities with inhibitory ratios of release of β-glucuronidase from polymorphonuclear leukocytes of rats in the range of 30.3—38.6% at 10 μM.

• 公益社団法人　日本薬学会の論文

著者

• Zhang De-wu

  School Of Pharmaceutical Science Yantai University

• Dai Sheng-jun

  School Of Pharmaceutical Science Yantai University

• Li Gui-Hai

  Shandong Academy of Chinese Medicine

• Yu Qun-Ying

  School of Pharmaceutical Science, Yantai University

関連論文

• Five New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities
• New Diels-Alder Type Adducts from Morus macroura and Their Anti-oxidant Activities
• Two New Sesquiterpenoids from Solanum lyratum with Cytotoxic Activities
• New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities
• New Anti-inflammatory 4-Hydroxyisoflavans from Solanum lyratum
• Four New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities

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