New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities
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概要
- 論文の詳細を見る
Four new neo-clerodane diterpenoid alkaloids, named scutebarbatines I-L (1-4), were isolated from the whole plant of Scutellaria barbata D. DON. Their structures were established on the basis of detailed spectral analyses. In vitro, the four new compounds showed significant cytotoxic activities against three human cancer lines (HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells), and gave IC_<50> values in the range 3.2-8.3μM.
- 公益社団法人日本薬学会の論文
- 2008-02-01
著者
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Ren Yan
School Of Pharmaceutical Science Yantai University
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Shen Li
Key Laboratory Of Marine Drugs Chinese Ministry Of Education Institute Of Marine Drug And Food
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Dai Sheng-jun
School Of Pharmaceutical Science Yantai University
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LIANG Dong-Dong
School of Pharmaceutical Science, Yantai University
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LIU Ke
School of Pharmaceutical Science, Yantai University
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SHEN Li
School of Pharmaceutical Science, Yantai University
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Liu Ke
School Of Pharmaceutical Science Yantai University
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Liang Dong-dong
School Of Pharmaceutical Science Yantai University
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