Two New Sesquiterpenoids from Solanum lyratum with Cytotoxic Activities

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概要

• 論文の詳細を見る

• Two new sesquiterpenoids, lyratol C (1) and lyratol D (2), together with two known sesquiterpenoids, dehydrovomifoliol (3) and blumenol A (4), were isolated from the whole plant of Solanum lyratum. Their structures were established by spectroscopic analyses. In vitro, the four compounds showed significant cytotoxic activities against three human cancer cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and gave IC_<50> values in the range 3.7-8.1μM.

• 公益社団法人日本薬学会の論文
• 2009-04-01

著者

• Ren Yan

  School Of Pharmaceutical Science Yantai University

• Shen Li

  Key Laboratory Of Marine Drugs Chinese Ministry Of Education Institute Of Marine Drug And Food

• Zhang De-wu

  School Of Pharmaceutical Science Yantai University

• Dai Sheng-jun

  School Of Pharmaceutical Science Yantai University

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• Two New Sesquiterpenoids from Solanum lyratum with Cytotoxic Activities
• New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities
• New Anti-inflammatory 4-Hydroxyisoflavans from Solanum lyratum
• Four New neo-Clerodane Diterpenoid Alkaloids from Scutellaria barbata with Cytotoxic Activities

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