Flavanoids and Pterocarpans from the Bark of Erythrina fusca
スポンサーリンク
概要
- 論文の詳細を見る
Three new isomeric flavanones, fuscaflavanones A1 (1), A2 (2) and B (3), together with six known flavanones, lupinifolin (4), lonchocarpol A (5), a mixture of lonchocarpols C1 and C2 (6a, b), and a mixture of lonchocarpols D1 and D2 (7a, b), five pterocarpans, sandwicensin (8), phaseollidin (9), erythrabissin I (10), and a mixture of dolichins A and B (11a, b), one chalcone, isobavachalcone (12), and one isoflavone, wighteone (13), were isolated from the bark of Erythrina fusca LOUR. Their structures were elucidated on the basis of spectroscopic data. Some isolates were tested for antiplasmodial and cytotoxic activities and it was found that 5 and 9 exhibited moderate antiplasmodial activity against Plasmodium falciparum. For cytotoxicity, compounds 1, 4, 5, 9 and 12 showed moderate to weak activity against KB, BC and NCI-H187 cells, whereas 2 exhibited only weak activity against KB cells.
- 公益社団法人 日本薬学会の論文
著者
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Suksamrarn Apichart
Department Of Chemistry And Center Of Excellence For Innovation In Chemistry Faculty Of Science Ramk
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Rukachaisirikul Thitima
Department Of Chemistry Faculty Of Science Ramkhamhaeng University
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Innok Phongsak
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng Uni
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Rukachaisirikul Thitima
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University
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Innok Phongsak
Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Ramkhamhaeng University
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