Antimycobacterial Activity of Prenylated Xanthones from the Fruits of Garcinia mangostana

スポンサーリンク

概要

• 論文の詳細を見る

• Prenylated xanthones, isolated from the fruit hulls and the edible arils and seeds of Garcinia mangostana, were tested for their antituberculosis potential, α- and β-Mangostins and garcinone B exhibited strong inhibitory effect against Mycobacterium tuberculosis with the minimum inhibitory concentration (MIC) value of 6.25/μg/ml. Tri- and tetra-oxygenated xanthones with di-C_5 units or with a C_5 and a modified C_5 groups are essential for high activities. Substitution in the A and C rings has been shown to modify the bioactivity of the compounds.

• 公益社団法人日本薬学会の論文
• 2003-07-01

著者

• Suksamrarn A

  Department Of Chemistry Faculty Of Science Ramkhamhaeng University

• Suksamrarn Apichart

  Department Of Chemistry And Center Of Excellence For Innovation In Chemistry Faculty Of Science Ramk

• SUKSAMRARN Sunit

  Department of Chemistry, Faculty of Science, Srinakharinwirot University

• RATANANUKUL Piniti

  Department of Chemistry, Faculty of Science, Srinakharinwirot University

• CHIMNOI Nitirat

  Chulabhorn Research Institute

• SUWANNAPOCH Narisara

  Department of Chemistry, Faculty of Science, Srinakharinwirot University

• PHAKHODEE Wong

  Department of Chemistry, Faculty of Science, Srinakharinwirot University

• THANUHIRANLERT Janthana

  Department of Chemistry, Faculty of Science, Srinakharinwirot University

• Ratananukul Piniti

  Department Of Chemistry Faculty Of Science Srinakharinwirot University

• Suksamrarn Sunit

  Department Of Chemistry Faculty Of Science Srinakharinwirot University

• Suwannapoch Narisara

  Department Of Chemistry Faculty Of Science Srinakharinwirot University

• Phakhodee Wong

  Department Of Chemistry Faculty Of Science Srinakharinwirot University

• Thanuhiranlert Janthana

  Department Of Chemistry Faculty Of Science Srinakharinwirot University

関連論文

• Effect of phloracetophenone on bile flow and biliary lipids in rats
• Antimycobacterial and Antiplasmodial Unsaturated Carboxylic Acid from the Twigs of Scleropyrum wallichianum
• (+)-Bornyl Piperate, a New Monoterpene Ester from Piper aff. pedicellatum Roots
• Bioactive Flavonoids of the Flowers of Butea monosperma
• Antimycobacterial Activity of Cinnamate-Based Esters of the Triterpenes Betulinic, Oleanolic and Ursolic Acids
• Flavanoids and Pterocarpans from the Bark of Erythrina fusca
• Cytotoxic Prenylated Xanthones from the Young Fruit of Garcinia mangostana
• Antimycobacterial Activity of Prenylated Xanthones from the Fruits of Garcinia mangostana
• Bioactive Constituents of the Root Bark of Artocarpus rigidus subsp. rigidus
• Ceanothane- and Lupane-Type Triterpenes with Antiplasmodial and Antimycobacterial Activities from Ziziphus cambodiana
• Novel Action of the Chalcone Isoliquiritigenin as a Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Inhibitor : Potential Therapy for Cholera and Polycystic Kidney Disease
• Pharmacokinetics and organ distribution of diarylheptanoid phytoestrogens from Curcuma comosa in rats
• Activation of AMP-Activated Protein Kinase by a Plant-Derived Dihydroisosteviol in Human Intestinal Epithelial Cell

もっと見る 閉じる

スポンサーリンク