Intensive Chemotherapy for a Patient with Primary Cutaneous Diffuse Large B-cell Lymphoma with Burkitt-like Morphology
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概要
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We report a rare case of primary cutaneous diffuse large B-cell lymphoma (DLBCL) with Burkitt-like morphology. A 54-year-old man presented with multiple subcutaneous tumors. Pathological examination showed morphological features resembling Burkitt or Burkitt-like lymphoma (BL/BLL) with high MIB-1 positivity. Cytogenetic studies revealed no 8q24/c-myc translocation. After the diagnosis of Burkitt-like DLBCL, the patient was treated with CODOX-M chemotherapy (cyclophosphamide, doxorubicin, vincristine, cytarabine and methotrexate), which led to durable remission. The present case suggests that short-term, high-intensity chemotherapy used for BL/BLL may be appropriate for primary cutaneous Burkitt-like DLBCL, as well as systemic lymphoma with Burkitt-like morphology.
著者
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Takasu Nobuyuki
Department Of Endocrinology And Metabolism Department Of Internal Medicine University Of The Ryukyus
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Nagasaki Akitoshi
Department Of Endocrinology And Metabolism Department Of Internal Medicine University Of The Ryukyus
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Ohshima Koichi
Department Of Cell Pathology Graduate School Of Medical Sciences Kumamoto University
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Okudaira Taeko
Department of Endocrinology and Metabolism, Internal Medicine, University of The Ryukyus School of Medicine
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Miyagi Takashi
Department of Endocrinology and Metabolism, Internal Medicine, University of The Ryukyus School of Medicine
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Taira Tamiko
Department of Endocrinology and Metabolism, Internal Medicine, University of The Ryukyus School of Medicine
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