Adult Patient with Epstein-Barr Virus (EBV)-Associated Lymphoproliferative Disorder: Chronic Active EBV Infection or de novo Extranodal Natural Killer (NK)/T-cell Lymphoma, Nasal Type?
スポンサーリンク
概要
- 論文の詳細を見る
Chronic active Epstein-Barr virus (EBV) infection, which is considered to be a childhood disease, often develops into natural killer (NK) or T-cell lymphoma after recurrent infectious mononucleosis (IM)-like symptoms. We describe a 56-year-old woman who developed NK-cell lymphoma after 9 months of recurrent IM-like symptoms. The patient had an unusual anti-EBV antibody profile. Increased levels of EBV genome were detected in the liver and peripheral blood. Several chemotherapy regimens were ineffective, and the patient died of progression of lymphoma. Certain subtypes of NK-cell lymphoma showing a long-lasting prodrome related to chronic EBV infection may exist.
- 社団法人 日本内科学会の論文
著者
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Abe Yasunobu
Department Of Medicine And Bioregulatory Science Graduate School Of Medical Science Kyushu Universit
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Sada Eriko
Department Of Medicine And Bioregulatory Science Graduate School Of Medical Sciences Kyushu Universi
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Takayanagi Ryoichi
Department Of Geriatric Medicine Graduate School Of Medical Sciences Kyushu University
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Shiratsuchi Motoaki
Department Of Internal Medicine National Kyushu Center Hospital
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Nishimura Junji
Department Of Clinical Immunology Medical Institute Of Bioregulation Kyushu University
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Ohtsuka Rie
Department Of Medicine And Bioregulatory Science Graduate School Of Medical Sciences Kyushu Universi
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Ohshima Koichi
Department Of Cell Pathology Graduate School Of Medical Sciences Kumamoto University
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Kiyasu Junichi
Department Of Internal Medicine And Rheumatology Clinical Research Center National Hospital Organization Kyushu Medical Center
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ABE Yasunobu
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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SHIRATSUCHI MOTOAKI
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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KIYASU Junichi
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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SADA Eriko
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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Ashikari Akiyo
Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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