Primary Aldosteronism Associated with Severe Rhabdomyolysis Due to Profound Hypokalemia

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概要

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• A 55-year-old Japanese man was admitted to our hospital with severe weakness. Without measurement of serum electrolyte concentrations, diuretic therapy for hypertension was started 2 weeks prior to admission. Laboratory findings showed profound hypokalemia (1.4 mEq/L), and extreme elevation of the serum creatinine phosphokinase levels (15,760 IU/L), suggesting that the patient had hypokalemic paralysis and hypokalemia-induced rhabdomyolysis. Further evaluations, including adrenal venous sampling strongly suggested that he had primary aldosteronism. He was treated successfully by laparoscopic adrenalectomy. This case provides an important lesson that serum electrolyte concentrations should be measured in hypertensive patients before the administration of antihypertensive agents.

著者

• Aibe Hitoshi

  Department Of Clinical Radiology Graduate School Of Madical Sciences Kyushu University

• Minowada Shigeru

  Department Of Urology Faculty Of Medicine The University Of Tokyo

• Kajio Hiroshi

  Department Of Cardiovascular Medicine Heart Failure Division National Cerebral And Cardiovascular Ce

• Hasuo Kanehiro

  Department Of Radiology Faculty Of Medicine Kyushu University

• Goto Atsushi

  Department Of Diabetes And Metabolic Medicine International Medical Center Of Japan

• Kishimoto Miyako

  Department Of Diabetes And Metabolic Medicine International Medical Center Of Japan

• Noda Mitsuhiko

  Department Of Diabetes And Metabolic Medicine Diabetes Research Center National Center For Global Health And Medicine

• TAKAHASHI YOSHIHIKO

  Department of Diabetes and Metabolic Medicine, International Medical Center of Japan

• MINOWADA SHIGERU

  Department of Urology, International Medical Center of Japan

• TAKAHASHI YOSHIHIKO

  Department of Anatomy Kurume, University School of Medicine

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