Involvement of the Esophagus and Stomach as a First Manifestation of Varicella Zoster Virus Infection after Allogeneic Bone Marrow Transplantation

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概要

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• A 46-year-old man with myeloproliferative disorder received a stem cell transplant from an HLA-identical unrelated donor. Eight months status post transplantation, during the course of tacrolimus therapy, the patient developed severe epigastric pain and fever. FGS findings showed eruptions with blisters in the esophagus and ulcers in the stomach. Biopsy specimens revealed acidophilic inclusion bodies in the nuclei. Varicella zoster virus (VZV) DNA copies were detected in the serum. No skin lesions were observed prior to hospital admission. The diagnosis of visceral VZV infection was made and the gastric and esophageal lesions were successfully healed with acyclovir (ACV). Severe abdominal pain is one of the most important signs of VZV infection for recipients of stem cell transplantation.

• 社団法人　日本内科学会の論文
• 2004-09-01

著者

• NAGAI Tadashi

  Division of Hematology, Jichi Medical University

• Nagai Tadashi

  東京慈恵会医科大学 内科学講座血液内科

• Nagai Tadashi

  Division Of Hematology Department Of Medicine Jichi Medical University

• KOMATSU Norio

  Division of Hematology, Department of Internal Medicine, Jichi Medical University

• Ozawa Keiya

  Division of Genetic Therapeutics, Jichi Medical School

• Muroi Kazuo

  Division of Cell Transplantation and Transfusion, Jichi Medical School

• Nagasawa Toshiro

  自治医科大学 医学部血液学

• Nagai T

  Division Of Hematology Department Of Medicine Jichi Medical University

• Muroi Kazuo

  Division Of Hematology Department Of Medicine Jichi Medical University

• Muroi Kazuo

  The Department Of Hematology

• Muroi Kazuo

  Division Of Cell Transplantation And Transfusion Jichi Medical School

• Ozawa Keiyo

  Department Of Hematology Jichi Medical School

• Kawano (yamamoto)

  Division Of Cell Transplantation And Transfusion Jichi Medical School

• Toshima Masaki

  Division Of Hematology Department Of Medicine Jichi Medical University

• TAKATOKU Masaaki

  Division of Hematology, Jichi Medical School

• Nagai Tadashi

  Department Of Biochemistry Tohoku University Graduate School Of Medicine

• Nagasawa T

  Division Of Hematology Institute Of Clinical Medicine University Of Tsukuba

• Ozawa K

  Division Of Hematology Department Of Medicine Jichi Medical University

• Komatsu Norio

  Department Of Hematology University Of Yamanashi

• Komatsu Norio

  Division Of Hematology Department Of Internal Medicine Jichi Medical University

• Ozawa Keiya

  Division Of Genetic Therapeutics Center For Molecular Medicine Jichi Medical School Crest Japan Scie

• Ozawa Keiya

  Division Of Genetic Therapeutics Center For Molecular Medicine Department Of Medicine Jichi Medical

• Ozawa Keiya

  Division Of Genetic Therapeutics Center For Molecular Medicine

• TAKATOKU Masaaki

  Division of Hematology, Department of Medicine, Jichi Medical School

• Muroi Kazuo

  Division of Cell Therapy, Jichi Medical University Hospital

• KAWANO-YAMAMOTO Chizuru

  Division of Cell Transplantation and Transfusion, Jichi Medical School

• Ozawa Keiya

  Division of Cell Therapy, Jichi Medical University Hospital, Shimotsuke

• Nagai Tadashi

  Division of Cell Therapy, Jichi Medical University Hospital, Shimotsuke

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