Effect of Emergency Percutaneous Coronary Intervention on In-Hospital Mortality of Very Elderly (80+ Years of Age) Patients With Acute Myocardial Infarction
スポンサーリンク
概要
- 論文の詳細を見る
It is still controversial whether percutaneous coronary intervention (PCI) is effective in improving in-hospital survival in very elderly patients. Therefore, using data from the Tokai Acute Myocardial Infarction Study II, we studied the effect of emergency PCI on the in-hospital mortality of very elderly (80+ years of age) patients with acute myocardial infarction (AMI). The study was a prospective study of all consecutive patients admitted to the 15 acute care hospitals in the Tokai region with the diagnosis of AMI from 2001 to 2003. A total of 211 patients undergoing emergency PCI and 176 patients not undergoing PCI were included in the present analysis. We compared the baseline and procedural characteristics and the clinical outcomes between the 2 groups. Patients without emergency PCI were older and had an increased prevalence of female gender, ADL impairment, and dementia in comparison with those with PCI. They also showed poorer clinical conditions. They were less likely to be transferred to intensive care or coronary care units and to be given intra-aortic balloon pumps. The patients with emergency PCI had nearly one-third the in-hospital mortality rate of the patients without emergency PCI. According to multivariate analysis, emergency PCI was still identified as an independent predictor of in-hospital death, with an adjusted odds ratio of 0.26 (95% CI, 0.07-0.97). The results indicated that emergency PCI has a preventative effect on in-hospital mortality in Japanese AMI patients 80 years of age and older.
- International Heart Journal刊行会の論文
著者
-
Hirakawa Yoshihisa
Department of Geriatrics, Nagoya University Graduate School of Medicine
-
Kimata Takaya
Department Of Geriatrics Nagoya University Graduate School Of Medicine
-
Iguchi Akihisa
Department Of Geriatrics Medicine In Growth And Aging Program In Health And Community Medicine Nagoy
-
Masuda Yuichiro
Department Of Geriatrics Nagoya University Graduate School Of Medicine
-
Kuzuya Masafumi
Department Of Community Healthcare And Geriatrics Nagoya University Graduate School Of Medicine
-
Uemura Kazumasa
Departments of Internal Medicine, Nagoya University Graduate School of Medicine
関連論文
- Age Differences in the Delivery of Cardiac Management to Women Versus Men With Acute Myocardial Infarction : An Evaluation of the TAMIS-II Data
- PE-166 Superoxide-Dependent Activation of Cathepsin System is Associated with Hypertensive Myocardial Remodeling and Represents a Target for AT1R Blocker Therapy(Cardiovascular pharmacology, basic/clinical(03)(H),Poster Session(English),The 72nd Annual Sc
- PE-343 A Elastolytic Cathepsin Induction/Activation System Exists in the Rat and Human Myocardium and is Upregulated in Hypertensive Heart Failure(Heart failure, clinical-09, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-179 Mechanisms Underlying the Impairment of Ischemia-induced Neovascularization in Aging Mice : the Pivotal Role for Matirx-Metalloproteinase-2(Regeneration(angiogenesis/myocardial regeneration)(04)(M),Poster Session(Japanese),The 72nd Annual Scientifi
- PJ-039 Treatment of ApoE-Deficient Mice with Statin Inhibits the Oxidative Stress-dependent Lysosomal Protease Cathepsin Activation System : Implication for Plaque Stability(Atherosclerosis, basic(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientif
- 2 Mechanisms underlying the impairment of ischemia-induced neovascularization in MMP-2-deficient mice(The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Nitric oxide : a negative feedback on endothelium-derived vascular relaxing factors
- White matter lesions as a feature of cognitive impairment, low vitality and other symptoms of geriatric syndrome in the elderly
- Simvastatin Improves Endothelial Function Due to Its Effects on Lipids and Pleiotropic Effects in Patients With Chronic Hemodialysis(Lipid Disorders 4 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- 1 Expression of the Lysosomal Cysteine Proteases Cathepsin S in the Left Ventricular Myocardium of Rats and Humans and Its Regulation in Cardiac Myocytes(Young Investigator's Award for International Students Finalists Lecture,The 70th Anniversary Annual S
- PJ-706 MMP-2 Deficiency Attenuates Ischemia-induced Angiogenesis and Vasculogenesis in MMP-2-Deficient Mice(Regeneration (angionenesis/myocardial regeneration)-7 (M) PJ119,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Jap
- OJ-178 Simvastatin Prevents Thrombotic Occlusion of Arterio-Venous Shunt in Dialysis Patients And Improves Endothelial Function Due to Its Pleiotropic Effects(Peripheral Circulation/Vascular Disease 1 (H) : OJ21)(Oral Presentation (Japanese))
- Favorable Life-Style Modification and Attenuation of Cardiovascular Risk Factors
- Association between insulin resistance and cognitive function in elderly diabetic patients
- OJ-189 Transplantation of Matrix Metalloproteinase-2-deficient Bone Marrow Inhibits Atherosclerotic Lesion Formation in Low Density Lipoprotein Receptor-deficient Mice(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presentation (Japanese))
- Importance of Lipid Levels in Elderly Diabetic Individuals : Baseline Characteristics and 1-Year Survey of Cardiovascular Events
- Effects of Gliclazide on Low-density Lipoprotein Oxidizability and Atherosclerosis in Cholesterol-fed Rabbits
- The Pressor Response Induced by Repeated Injections of Neostigmine into the Central Nervous System is Desensitized in Adrenalectomized, But Not in Intact Rats
- Central Nervous System-Mediated Hyperglycemic Effects of NIK-247, a Cholinesterase Inhibitor, and MKC-231, a Choline Uptake Enhancer, in Rats
- Age-related Differences in the Delivery of Cardiac Management to Women Versus Men With Acute Myocardial Infarction in Japan : Tokai Acute Myocardial Infarction Study: TAMIS
- Long-term prognosis and satisfaction after percutaneous endoscopic gastrostomy in a general hospital
- Emergency department use by nonagenarian patients
- Possibility of the regression of atherosclerosis through the prevention of endothelial senescence by the regulation of nitric oxide and free radical scavengers
- Bowel incontinence is related to improvement in basic activities of daily living in residents of long-term health care facilities for the elderly in Japan
- Factors influencing death at home in terminally ill cancer patients
- Sarpogrelate HCI, a selective 5 HT_2A antagonist, retards progression of atherosclerosis through novel mechanism other than NO-reactive oxygen species
- Mechanism of regression of advanced atherosclerosis by in vivo gene transfer of eNOS, but not iNOS or eNOS plus iNOS
- A HMG-CoA reductase inhibitor, NK-104 possess retards high cholesterol induced atherosclerosis in rabbits relevance of nitric oxide and superoxide anion
- IS088 A HMG-CoA Reducatase Inhibitor Improved Regression of Atherosclerosis in the Rabbit Aorta Whithout Affecting Serum Lipid Levels : Relevance of Up Regulation of Endothelial NO Synthase
- IS062 Change of Endothelial Dependent and Independent Vascular Response in Aged Diabetic Rats : The Relation of eNOS and Soluble Guanylate Cyclase Activity
- IS111 Peroxynitrite(ONOO)impaired the restoration of endothelium-dependent relaxation of rabbit atherosclerotic aorta by control of hyperlipidemia
- The Effect and Meaning of Estrogen on Telomerase Activity in Cultured Endothelial Cells : Implication For Effect of Aging on Atherosclerosis(Atherosclerosis, Basic 8 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Estrogen Improves the eNOS Dysfunction in Hyperglycemia-Implication for Anti-atherosclerotic Effect of Estrogen in Diabetes(Metabolic Syndrome (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-485 The high incidence of ischemic coronary lesion in elderly diabetics and the efficient prediction by the exercise tolerance test(Exercise Test/Cardiac Rehabilitation 5 (IHD) : PJ81)(Poster Session (Japanese))
- PE-456 Celiprolol hydrochloride, β1 antagonist, β2 agonist, retards progression of vascular lesions and restores endothelial dysfunction in Type II Diabetic rats(Diabetes/Obesity 4 (H) : PE78)(Poster Session (English))
- PE-289 BMP level is diagnostic for heart failure in elderly, however IL-6,TNFα or NO is important in bedridden or renal failure(Heart Failure, Clinical 11 (M) : PE50)(Poster Session (English))
- Vascular Citrulline-Arginine Cycle Plays a Role in the Antiatherosclerotic Effect of 17β Estradiol on the High Cholesterol Diet Induced Atherosclerosis
- Plasma Adiponectin Plays an Important Role in Improvement of Insulin Resistance and Inhibit Atherogenesis by Glimepiride in Elderly Diabetics
- Oxygen Radical Scavenger, Apocynin Retarads Progression of Vascular Lesion and Improve Endothelial Dysfunction in Type II Diabetic Rats
- 0321 Impairment of endothelium-dependent relaxation in the advanced rabbit atherosclerotic aorta could not be reversed even after long term of normal diet.
- -1383- The role of 17β-estradiol on production of nitric oxide and inducible form of nitric oxide synthase in J774 cells(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- -1382- The effect of estrogen on neuronal and endothelial constitutive nitric oxide synthase(PROCEEDINGS OF THE 59th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY)
- Gender differences in atherosclerosis formation: Possible role of nitric oxide
- -1132-LDL IMPAIRS ENDOTHELIUM-DEPENDENT RELAXATION ESPECIALLY IN HYPERLIPIDEMIC PORCINE CORONARY ARTERIES : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Cardiac remodeling after myocardial infarction in mice lacking matrix metalloproteinase-2 (MMP-2)
- Gender-Related Difference in Relationship between Insulin Resistance and Serum Leptin Level in Japanese Type 2 Diabetic and Non-Diabetic Subjects
- Philadelphia Geriatric Center morale scale in a Japanese nursing home for the elderly
- 在宅介護における介護負担感の性差に関する調査 : 名古屋市在住の要介護高齢者における縦断研究の結果から
- Impact of Gender on In-Hospital Mortality of Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention: An Evaluation of the TAMIS-II Data
- Association between masticatory performance and anthropometric measurements and nutritional status in the elderly
- Neutrophil elastase in pressure ulcer fluid degrades fibronectin in the exudates
- Complications Following Percutaneous Endoscopic Gastrostomy : Acute Respiratory Infection and Local Skin Infection
- Role of Matrix Metalloproteinases in Vascular Remodeling
- 1 High Incidence of Vascular Events in Japanese Diabetics : The Effect of Lowering LDL and the Direct Effect of Anti-hyperlipidemic Drugs(Diabetic Cardiovascular Complications and Therapeutic Strategy, The 71st Annual Scientific Meeting of the Japanese Ci
- Influence of diabetes mellitus on caregiver burden in home care : A report based on the Nagoya Longitudinal Study of the Frail Elderly (NLS-FE)
- Non-medical palliative care and education to improve end-of-life care at geriatric health services facilities : A nationwide questionnaire survey of chief nurses
- Factors associated with use of percutaneous coronary intervention among very elderly patients with acute myocardial infarction : Lessons from the Tokai Acute Myocardial Infarction Study (TAMIS)
- Director perceptions of end-of-life care at geriatric health services facilities in Japan
- Age-related differences in clinical characteristics, early outcomes and cardiac management of acute myocardial infarction in Japan : Lessons from the Tokai Acute Myocardial Infarction Study (TAMIS)
- Age-related differences in care receipt and symptom experience of elderly cancer patients dying at home : Lessons from the DEATH project
- Factors associated with change in walking ability in very elderly patients hospitalized for acute myocardial infarction
- Influence of nutritional status on early outcomes of elderly patients admitted with acute myocardial infarction
- End-of-life experience of demented elderly patients at home : findings from DEATH project
- S-1 Nutritional aspects and healthy ageing : preventing geriatric syndrome(The Proceedings of the 15th Annual Meetings of Japan Society of Exercise and Sports Physiology July 26-27, (Hirosaki))
- Sensitive Pupil Response of Early-Onset Alzheimer's Patients to a Dilute Mixture of Cholinergic Antagonist and α-Adrenergic Stimulant
- Survey on geriatricians' experiences of adverse drug reactions caused by potentially inappropriate medications : Commission report of the Japan Geriatrics Society
- Plasma insulin and glucose levels in elderly female subjects with Alzheimer's disease
- -1125-EFFECTS OF FIBRINOGEN AND FIBRIN ON THE MIGRATION OF VASCULAR SMOOTH MUSCLE CELLS N VITRO : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- THE EFFECT OF DENATURED LOW DENSITY LIPOPROTEINS ON THE MIGRATION OF VASCULAR SMOOTH MUSCLE CELLS IN CULTURE : Arteriosclerosis : 53 Annual Scientific Meeting, Japanese Circulation Society
- -111-β VERY LOW DENSITY LIPOPROTEIN ATTENUATES ENDOTHELIUM DEPENDENT RELAXATION IN RABBIT ATHEROSCLEROTIC VESSELS : Cardiovascular Drugs : FREE COMMUNICATIONS(I) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- ISOLATION AND CHARACTERIZATION OF FOAM CELLS IN ATHEROSCLEROTIC LESIONS : Atherosclerosis : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- VASCULAR ENDOTHELIAL CELL (EC) AND SMOOTH MUSCLE CELL (SMC) MIGRATION IN VITRO : Blood Vessels : FREE COMMUNICATIONS (I) : PROCEEDINGS OF THE 49th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Mechanisms of Endothelial Cell Injury Induced by Oxidatively Modified LDL
- Guidelines for non-medical care providers to manage the first steps of emergency triage of elderly evacuees
- Effects of Dexamethasone on Experimental Atherosclerosis in Cholesterol-fed Rabbits.
- Dietary Reference Intakes for Japanese 2010: Lifestage
- Association of Renal Insufficiency With In-Hospital Mortality Among Japanese Patients With Acute Myocardial Infarction Undergoing Percutaneous Coronary Interventions
- Absence of Outcome Difference in Elderly Patients With and Without Dementia After Acute Myocardial Infarction An Evaluation of TAMIS-II Data:An Evaluation of TAMIS-II Data
- Effect of Emergency Percutaneous Coronary Intervention on In-Hospital Mortality of Very Elderly (80+ Years of Age) Patients With Acute Myocardial Infarction
- Japanese Patients With Acute Myocardial Infarction Who Present Without Chest Pain A High-risk Group:A High-risk Group
- Day-care service use is a risk factor for long-term care placement in community-dwelling dependent elderly