慢性腎不全患者に施行したピラルビシン膀胱内注入療法の1例

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71歳女.慢性腎不全患者に発生した膀胱腫瘍にTHPの膀胱内注入を行い,血中・血球内ともに0.010μg/ml以下と低く,臨床的に副作用を起こすほどの濃度ではなかったThe patient was a 71-year-old woman. Two years ago right nephrectomy was performed by a general surgeon at the diagnosis of right renal cell carcinoma. However, the pathological report was transitional cell carcinoma (TCC) of the right renal pelvis, Grade II. She developed chronic renal failure and received hemodialysis once a week. The recurrence of bladder tumor was recognized and she was transferred to our hospital. Transurethral resection of bladder tumor (TUR-Bt) and right ureterectomy with a bladder cuff were performed. Also intravesical instillation of pirarubicin was done after the operation. No side effects or elevation of serum pirarubicin level were observed.